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- 3,4-Dihydroxyphenylacetic_acid abstract "3,4-Dihydroxyphenylacetic acid (DOPAC) is a metabolite of the neurotransmitter dopamine. Dopamine can be metabolized into one of three substances. One such substance is DOPAC. Another is 3-methoxytyramine (3-MT). Both of these substances are degraded to form homovanillic acid (HVA). Both degradations involve the enzymes monoamine oxidase (MAO) and catechol-O-methyl transferase (COMT), albeit in reverse order: MAO catalyzes dopamine to DOPAC, and COMT catalyzes DOPAC to HVA; whereas COMT catalyzes dopamine to 3-MT and MAO catalyzes 3-MT to HVA. The third metabolic end-product of dopamine is norepinephrine (noradrenaline).DOPAC can be oxidized by hydrogen peroxide, leading to the formation of toxic metabolites which destroy dopamine storage vesicles in the substantia nigra. This may contribute to the failure of levodopa treatment of Parkinson's disease. A MAO-B inhibitor such as selegiline or rasagiline can prevent this from happening.It can also be found in the bark of Eucalyptus globulus.This product has been synthesized (52% yield) from 4-Hydroxyphenylacetic acid via aerobic biotransformation using whole cell cultures of Arthrobacter protophormiae.".
- 3,4-Dihydroxyphenylacetic_acid iupacName "2-(3,4-Dihydroxyphenyl)acetic acid".
- 3,4-Dihydroxyphenylacetic_acid thumbnail 3,4-Dihydroxyphenylacetic_acid.svg?width=300.
- 3,4-Dihydroxyphenylacetic_acid wikiPageID "3230594".
- 3,4-Dihydroxyphenylacetic_acid wikiPageLength "4071".
- 3,4-Dihydroxyphenylacetic_acid wikiPageOutDegree "26".
- 3,4-Dihydroxyphenylacetic_acid wikiPageRevisionID "670370820".
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink 3-Methoxytyramine.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink 3-methoxytyramine.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink 4-Hydroxyphenylacetic_acid.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Aerobic_organism.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Arthrobacter_protophormiae.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Biotransformation.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Catechol-O-methyl_transferase.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Category:Acetic_acids.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Category:Catechols.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Category:Natural_phenols.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Category:Phenolic_human_metabolites.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Dopamine.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Enzyme_inhibitor.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Eucalyptus_globulus.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Homovanillic_acid.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Hydrogen_peroxide.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink L-DOPA.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Levodopa.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Metabolite.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Monoamine_oxidase.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Monoamine_oxidase_B.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Neurotransmitter.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Norepinephrine.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Parkinsons_disease.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Rasagiline.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Selegiline.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink Substantia_nigra.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLink File:Dopamine_degradation.svg.
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLinkText "3,4-Dihydroxyphenylacetic acid".
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLinkText "3,4-dihydroxyphenylacetic acid".
- 3,4-Dihydroxyphenylacetic_acid wikiPageWikiLinkText "DOPAC".
- 3,4-Dihydroxyphenylacetic_acid hasPhotoCollection 3,4-Dihydroxyphenylacetic_acid.
- 3,4-Dihydroxyphenylacetic_acid imagefile "34".
- 3,4-Dihydroxyphenylacetic_acid imagesize "200".
- 3,4-Dihydroxyphenylacetic_acid iupacname "2".
- 3,4-Dihydroxyphenylacetic_acid verifiedrevid "477217493".
- 3,4-Dihydroxyphenylacetic_acid watchedfields "changed".
- 3,4-Dihydroxyphenylacetic_acid wikiPageUsesTemplate Template:Chembox.
- 3,4-Dihydroxyphenylacetic_acid wikiPageUsesTemplate Template:Clear-left.
- 3,4-Dihydroxyphenylacetic_acid wikiPageUsesTemplate Template:Neurotransmitter_metabolism_intermediates.
- 3,4-Dihydroxyphenylacetic_acid wikiPageUsesTemplate Template:Reflist.
- 3,4-Dihydroxyphenylacetic_acid subject Category:Acetic_acids.
- 3,4-Dihydroxyphenylacetic_acid subject Category:Catechols.
- 3,4-Dihydroxyphenylacetic_acid subject Category:Natural_phenols.
- 3,4-Dihydroxyphenylacetic_acid subject Category:Phenolic_human_metabolites.
- 3,4-Dihydroxyphenylacetic_acid hypernym Metabolite.
- 3,4-Dihydroxyphenylacetic_acid type ChemicalCompound.
- 3,4-Dihydroxyphenylacetic_acid type ChemicalSubstance.
- 3,4-Dihydroxyphenylacetic_acid type ChemicalObject.
- 3,4-Dihydroxyphenylacetic_acid type Thing.
- 3,4-Dihydroxyphenylacetic_acid type Q11173.
- 3,4-Dihydroxyphenylacetic_acid comment "3,4-Dihydroxyphenylacetic acid (DOPAC) is a metabolite of the neurotransmitter dopamine. Dopamine can be metabolized into one of three substances. One such substance is DOPAC. Another is 3-methoxytyramine (3-MT). Both of these substances are degraded to form homovanillic acid (HVA).".
- 3,4-Dihydroxyphenylacetic_acid label "3,4-Dihydroxyphenylacetic acid".
- 3,4-Dihydroxyphenylacetic_acid sameAs ۳٬۴-دیهیدروکسیفنیلاستیک_اسید.
- 3,4-Dihydroxyphenylacetic_acid sameAs Ácido_3,4-di-hidroxifenilacético.
- 3,4-Dihydroxyphenylacetic_acid sameAs m.08_z4m.
- 3,4-Dihydroxyphenylacetic_acid sameAs 3,4-Dihidroksifenilsirćetna_kiselina.
- 3,4-Dihydroxyphenylacetic_acid sameAs 3,4-Dihidroksifenilsirćetna_kiselina.
- 3,4-Dihydroxyphenylacetic_acid sameAs Q4634071.
- 3,4-Dihydroxyphenylacetic_acid sameAs Q4634071.
- 3,4-Dihydroxyphenylacetic_acid wasDerivedFrom 3,4-Dihydroxyphenylacetic_acid?oldid=670370820.
- 3,4-Dihydroxyphenylacetic_acid depiction 3,4-Dihydroxyphenylacetic_acid.svg.
- 3,4-Dihydroxyphenylacetic_acid isPrimaryTopicOf 3,4-Dihydroxyphenylacetic_acid.