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- 124I-PGN650 abstract "124I-PGN650 is a phosphatidylserine (PS)-targeting F(ab’)2 fully human monoclonal antibody fragment (derived from PGN635) joined to the PET imaging radio-isotope iodine-124 (124I) that is currently evaluated in an exploratory trial for cancer imaging. PS is a molecule usually located inside the membrane of healthy cells, but "flips" and becomes exposed on the outside of cells that line tumor blood vessels, creating a specific target for the imaging of multiple solid tumor types. In preclinical studies, 124I-PGN650 accumulates in tumor vasculature and provides in vivo tumor images. Additionally, chemotherapies and radiation therapy increase the amount of exposed PS on tumor blood vessels.".
- 124I-PGN650 wikiPageExternalLink measuring-response-to-therapy-by-near-infrared-imaging-of-tumors-using-a-phosphatidylserine-targeting-antibody-fragment.
- 124I-PGN650 wikiPageExternalLink 1377.full.pdf+html.
- 124I-PGN650 wikiPageExternalLink nihms220242.pdf.
- 124I-PGN650 wikiPageExternalLink 22191000.
- 124I-PGN650 wikiPageExternalLink fetchObject.action?uri=info%3Adoi%2F10.1371%2Fjournal.pone.0084864&representation=PDF.
- 124I-PGN650 wikiPageID "44508191".
- 124I-PGN650 wikiPageLength "4283".
- 124I-PGN650 wikiPageOutDegree "17".
- 124I-PGN650 wikiPageRevisionID "666099452".
- 124I-PGN650 wikiPageWikiLink Category:Isotopes_of_iodine.
- 124I-PGN650 wikiPageWikiLink Category:Monoclonal_antibodies.
- 124I-PGN650 wikiPageWikiLink Category:Phospholipids.
- 124I-PGN650 wikiPageWikiLink Chemotherapies.
- 124I-PGN650 wikiPageWikiLink Chemotherapy.
- 124I-PGN650 wikiPageWikiLink Circulatory_system.
- 124I-PGN650 wikiPageWikiLink Dosimetry.
- 124I-PGN650 wikiPageWikiLink File:PGN650_Mouse_Tumor_Imaging_Descriptive_Image.png.
- 124I-PGN650 wikiPageWikiLink In_vivo.
- 124I-PGN650 wikiPageWikiLink Iodine-124.
- 124I-PGN650 wikiPageWikiLink Isotopes_of_iodine.
- 124I-PGN650 wikiPageWikiLink Medical_imaging.
- 124I-PGN650 wikiPageWikiLink Monoclonal_antibody.
- 124I-PGN650 wikiPageWikiLink Neoplasm.
- 124I-PGN650 wikiPageWikiLink PET_imaging.
- 124I-PGN650 wikiPageWikiLink Peregrine_Pharmaceuticals.
- 124I-PGN650 wikiPageWikiLink Phosphatidylserine.
- 124I-PGN650 wikiPageWikiLink Positron_emission_tomography.
- 124I-PGN650 wikiPageWikiLink Radiation_therapy.
- 124I-PGN650 wikiPageWikiLink Radio-isotope.
- 124I-PGN650 wikiPageWikiLink Radionuclide.
- 124I-PGN650 wikiPageWikiLink Solid_tumor.
- 124I-PGN650 wikiPageWikiLink Vasculature.
- 124I-PGN650 wikiPageWikiLinkText "124I-PGN650".
- 124I-PGN650 hasPhotoCollection 124I-PGN650.
- 124I-PGN650 wikiPageUsesTemplate Template:Cite_journal.
- 124I-PGN650 wikiPageUsesTemplate Template:Reflist.
- 124I-PGN650 subject Category:Isotopes_of_iodine.
- 124I-PGN650 subject Category:Monoclonal_antibodies.
- 124I-PGN650 subject Category:Phospholipids.
- 124I-PGN650 hypernym Phosphatidylserine.
- 124I-PGN650 comment "124I-PGN650 is a phosphatidylserine (PS)-targeting F(ab’)2 fully human monoclonal antibody fragment (derived from PGN635) joined to the PET imaging radio-isotope iodine-124 (124I) that is currently evaluated in an exploratory trial for cancer imaging. PS is a molecule usually located inside the membrane of healthy cells, but "flips" and becomes exposed on the outside of cells that line tumor blood vessels, creating a specific target for the imaging of multiple solid tumor types.".
- 124I-PGN650 label "124I-PGN650".
- 124I-PGN650 sameAs m.012c5nph.
- 124I-PGN650 sameAs Q19902996.
- 124I-PGN650 sameAs Q19902996.
- 124I-PGN650 wasDerivedFrom 124I-PGN650?oldid=666099452.
- 124I-PGN650 isPrimaryTopicOf 124I-PGN650.