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- 1-Methylpsilocin abstract "1-Methylpsilocin is a tryptamine derivative which acts as a selective agonist for the 5-HT2C receptor (IC50 of 12 nM, vs 633 nM at 5-HT2A), and an inverse agonist at 5-HT2B (Ki of 38 nM). While 1-methylpsilocin does have higher affinity for 5-HT2C than 5-HT2A, it does produces a head-twitch response in mice that is dependent on 5-HT2A, so it is not entirely free of effects on 5-HT2A in vivo. In contrast to psilocin, 1-methylpsilocin did not activate 5-HT1A receptors in mice. 1-Methylpsilocin has been investigated for applications such as treatment of glaucoma, OCD, and cluster headaches, as these conditions are amenable to treatment with psychedelic drugs but are not generally treated with such agents due to the undesirable hallucinogenic side effects they produce. 1-Methylpsilocin therefore represents a potential alternative treatment to psilocin that may be less likely to produce hallucinogenic effects.".
- 1-Methylpsilocin casNumber "1465-16-3".
- 1-Methylpsilocin iupacName "1-Methyl-3-[2-(N,N-dimethylamino)ethyl]-4-hydroxyindole".
- 1-Methylpsilocin pubchem "44404883".
- 1-Methylpsilocin thumbnail 1-Methylpsilocin_structure.png?width=300.
- 1-Methylpsilocin wikiPageID "44501878".
- 1-Methylpsilocin wikiPageLength "3313".
- 1-Methylpsilocin wikiPageOutDegree "19".
- 1-Methylpsilocin wikiPageRevisionID "680138360".
- 1-Methylpsilocin wikiPageWikiLink 1-Methyl-5-methoxy-diisopropyltryptamine.
- 1-Methylpsilocin wikiPageWikiLink 2-Bromo-LSD.
- 1-Methylpsilocin wikiPageWikiLink 5-HT2A_receptor.
- 1-Methylpsilocin wikiPageWikiLink 5-HT2B_receptor.
- 1-Methylpsilocin wikiPageWikiLink 5-HT2C_receptor.
- 1-Methylpsilocin wikiPageWikiLink Agonist.
- 1-Methylpsilocin wikiPageWikiLink CP-132,484.
- 1-Methylpsilocin wikiPageWikiLink Category:Hydroxyarenes.
- 1-Methylpsilocin wikiPageWikiLink Category:Serotonin_receptor_agonists.
- 1-Methylpsilocin wikiPageWikiLink Category:Tryptamines.
- 1-Methylpsilocin wikiPageWikiLink Cluster_headache.
- 1-Methylpsilocin wikiPageWikiLink Cluster_headaches.
- 1-Methylpsilocin wikiPageWikiLink Glaucoma.
- 1-Methylpsilocin wikiPageWikiLink Head-twitch_response.
- 1-Methylpsilocin wikiPageWikiLink Inverse_agonist.
- 1-Methylpsilocin wikiPageWikiLink O-4310.
- 1-Methylpsilocin wikiPageWikiLink Obsessive–compulsive_disorder.
- 1-Methylpsilocin wikiPageWikiLink Psychedelic_drug.
- 1-Methylpsilocin wikiPageWikiLink Receptor_(biochemistry).
- 1-Methylpsilocin wikiPageWikiLink Tryptamine.
- 1-Methylpsilocin wikiPageWikiLinkText "1-Methylpsilocin".
- 1-Methylpsilocin c "13".
- 1-Methylpsilocin casNumber "1465".
- 1-Methylpsilocin h "18".
- 1-Methylpsilocin hasPhotoCollection 1-Methylpsilocin.
- 1-Methylpsilocin iupacName "1".
- 1-Methylpsilocin molecularWeight "218.294".
- 1-Methylpsilocin n "2".
- 1-Methylpsilocin o "1".
- 1-Methylpsilocin pubchem "44404883".
- 1-Methylpsilocin smiles "CNCCcc2c1cccc2O".
- 1-Methylpsilocin width "140".
- 1-Methylpsilocin wikiPageUsesTemplate Template:Drugbox.
- 1-Methylpsilocin wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- 1-Methylpsilocin wikiPageUsesTemplate Template:Reflist.
- 1-Methylpsilocin wikiPageUsesTemplate Template:Serotonergics.
- 1-Methylpsilocin wikiPageUsesTemplate Template:Tryptamines.
- 1-Methylpsilocin subject Category:Hydroxyarenes.
- 1-Methylpsilocin subject Category:Serotonin_receptor_agonists.
- 1-Methylpsilocin subject Category:Tryptamines.
- 1-Methylpsilocin type ChemicalSubstance.
- 1-Methylpsilocin type Drug.
- 1-Methylpsilocin type ChemicalObject.
- 1-Methylpsilocin type Thing.
- 1-Methylpsilocin type Q8386.
- 1-Methylpsilocin comment "1-Methylpsilocin is a tryptamine derivative which acts as a selective agonist for the 5-HT2C receptor (IC50 of 12 nM, vs 633 nM at 5-HT2A), and an inverse agonist at 5-HT2B (Ki of 38 nM). While 1-methylpsilocin does have higher affinity for 5-HT2C than 5-HT2A, it does produces a head-twitch response in mice that is dependent on 5-HT2A, so it is not entirely free of effects on 5-HT2A in vivo. In contrast to psilocin, 1-methylpsilocin did not activate 5-HT1A receptors in mice.".
- 1-Methylpsilocin label "1-Methylpsilocin".
- 1-Methylpsilocin sameAs m.012c5pvm.
- 1-Methylpsilocin sameAs Q19597906.
- 1-Methylpsilocin sameAs Q19597906.
- 1-Methylpsilocin wasDerivedFrom 1-Methylpsilocin?oldid=680138360.
- 1-Methylpsilocin depiction 1-Methylpsilocin_structure.png.
- 1-Methylpsilocin isPrimaryTopicOf 1-Methylpsilocin.