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(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane abstract "RTI-126 ((–)-2β-(1,2,4-oxadiazol-5-methyl)-3β-phenyltropane) is a phenyltropane derivative which acts as a potent monoamine reuptake inhibitor and stimulant drug. It is around 5 times more potent a stimulant than cocaine, but is relatively unselective. It binds to all three monoamine transporters, although still with some selectivity for the dopamine transporter. RTI-126 has a fast onset of effects and short duration of action, and its pharmacological profile in animals is among the closest to cocaine itself out of all the drugs in the RTI series. Its main application in scientific research has been in studies investigating the influence of pharmacokinetics on the abuse potential of stimulant drugs, with its rapid entry into the brain thought to be a key factor in producing its high propensity for development of dependence in animals.The structurally related compound (–)-2β-(3-methyl-5-isoxazolyl)nortropane is a potent and selective agonist for nicotinic acetylcholine receptors, with twice the potency of nicotine.".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane casNumber "146659-37-2".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane iupacName "(1R,2S,3S,5S)-8-methyl-2-(3-methyl-1,2,4-oxadiazol-5-yl)-3-phenyl-8-azabicyclo[3.2.1]octane".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane thumbnail RTI-126.png?width=300.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageID "18655261".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageLength "3787".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageOutDegree "16".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageRevisionID "668849324".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageWikiLink Category:Dopamine_reuptake_inhibitors.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageWikiLink Category:Oxadiazoles.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageWikiLink Category:RTI_compounds.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageWikiLink Category:Stimulants.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageWikiLink Category:Tropanes.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageWikiLink Cocaine.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageWikiLink Dopamine_transporter.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageWikiLink List_of_cocaine_analogues.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageWikiLink Monoamine.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageWikiLink Monoamine_neurotransmitter.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageWikiLink Nicotine.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageWikiLink Nicotinic_acetylcholine_receptor.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageWikiLink Pharmacokinetics.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageWikiLink Phenyltropane.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageWikiLink Reuptake_inhibitor.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageWikiLink Stimulant.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageWikiLink File:2β-(3-methyl-5-isoxazolyl)nortropane_structure.png.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageWikiLinkText "(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane c "17".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane casNumber "146659".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane h "21".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane hasPhotoCollection (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane iupacName "-8".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane legalStatus "Temporary Class Drug".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane molecularWeight "283.367".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane n "3".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane o "1".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane smiles "CN2C1CCC2CCC1c3ncon3".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane width "220".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageUsesTemplate Template:Dopaminergics.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageUsesTemplate Template:Drugbox.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageUsesTemplate Template:Nervous-system-drug-stub.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageUsesTemplate Template:Phenyltropanes.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageUsesTemplate Template:Reflist.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageUsesTemplate Template:Stimulants.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane subject Category:Dopamine_reuptake_inhibitors.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane subject Category:Oxadiazoles.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane subject Category:RTI_compounds.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane subject Category:Stimulants.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane subject Category:Tropanes.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane type ChemicalSubstance.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane type Drug.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane type ChemicalObject.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane type Thing.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane type Q8386.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane comment "RTI-126 ((–)-2β-(1,2,4-oxadiazol-5-methyl)-3β-phenyltropane) is a phenyltropane derivative which acts as a potent monoamine reuptake inhibitor and stimulant drug. It is around 5 times more potent a stimulant than cocaine, but is relatively unselective. It binds to all three monoamine transporters, although still with some selectivity for the dopamine transporter.".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane label "(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane".
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane sameAs (-)-2β-(1,2,4-Oxadiazol-5-méthyl)-3β-phényltropane.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane sameAs m.04gngw_.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane sameAs (-)-2β-(1,2,4-Oksadiazol-5-metil)-3β-feniltropan.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane sameAs (-)-2β-(1,2,4-Oksadiazol-5-metil)-3β-feniltropan.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane sameAs Q4540633.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane sameAs Q4540633.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wasDerivedFrom (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane?oldid=668849324.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane depiction RTI-126.png.
(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane isPrimaryTopicOf (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane.