Matches in DBpedia 2015-10 for { ?s ?p "Ether cleavage refers to chemical substitution reactions that lead to the cleavage of ethers. Due to the high chemical stability of ethers, ether cleavage is only possible under strongly acidic or extremely basic conditions.In organic chemistry, ether cleavage is an acid catalyzed nucleophilic substitution reaction. Depending on the specific ether, cleavage can follow either SN1 or SN2 mechanisms. Distinguishing between both mechanisms requires consideration of inductive and mesomeric effects that could stabilize or destabilize a potential carbocation in the SN1 pathway. Usage of Hydrohalic acids takes advantage of the fact that these agents are able to protonate the ether oxygen atom and also provide a halide anion as a suitable nucleophile. However, as ethers show similar basicity as alcohols (pKa of approximately 16), the equilibrium of protonation lies on the side of the unprotonated ether and cleavage is usually very slow at room temperature.In organometallic chemistry, ether cleavage refers to the decomposition of etheric solvents by extremely basic metallorganic agents. Cyclic ethers are especially susceptible to ether cleavage, but acyclic ethers can be cleaved as well."@en }
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- Ether_cleavage abstract "Ether cleavage refers to chemical substitution reactions that lead to the cleavage of ethers. Due to the high chemical stability of ethers, ether cleavage is only possible under strongly acidic or extremely basic conditions.In organic chemistry, ether cleavage is an acid catalyzed nucleophilic substitution reaction. Depending on the specific ether, cleavage can follow either SN1 or SN2 mechanisms. Distinguishing between both mechanisms requires consideration of inductive and mesomeric effects that could stabilize or destabilize a potential carbocation in the SN1 pathway. Usage of Hydrohalic acids takes advantage of the fact that these agents are able to protonate the ether oxygen atom and also provide a halide anion as a suitable nucleophile. However, as ethers show similar basicity as alcohols (pKa of approximately 16), the equilibrium of protonation lies on the side of the unprotonated ether and cleavage is usually very slow at room temperature.In organometallic chemistry, ether cleavage refers to the decomposition of etheric solvents by extremely basic metallorganic agents. Cyclic ethers are especially susceptible to ether cleavage, but acyclic ethers can be cleaved as well.".