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- Melanocyte-inhibiting_factor abstract "Melanocyte-inhibiting factor (also known as Pro-Leu-Gly-NH2, Melanostatin, MSH release-inhibiting hormone or MIF-1) is an endogenous peptide fragment derived from cleavage of the hormone oxytocin, but having generally different actions in the body. MIF-1 produces multiple effects, both blocking the effects of opioid receptor activation, while at the same time acting as a positive allosteric modulator of the D2 and D4 dopamine receptor subtypes, as well as inhibiting release of other neuropeptides such as alpha-MSH, and potentiating melatonin activity.This complex mix of actions produces a profile of antidepressant, nootropic, and anti-Parkinsonian effects when MIF-1 is administered, and it has been investigated for various medical uses. MIF-1 is unusually resistant to metabolism in the bloodstream, and crosses the blood–brain barrier easily, though it is poorly active orally and is usually injected. Several other closely related peptides with important actions in the body include Tyr-MIF-1 and endomorphin-1 and -2.".
- Melanocyte-inhibiting_factor bioavailability "100.0".
- Melanocyte-inhibiting_factor casNumber "2002-44-0".
- Melanocyte-inhibiting_factor iupacName "(S)-N-((S)-1-(2-amino-2-oxoethylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide".
- Melanocyte-inhibiting_factor pubchem "3896043".
- Melanocyte-inhibiting_factor thumbnail MIF-1_structure.png?width=300.
- Melanocyte-inhibiting_factor wikiPageID "32196844".
- Melanocyte-inhibiting_factor wikiPageRevisionID "592468704".
- Melanocyte-inhibiting_factor bioavailability "100.0".
- Melanocyte-inhibiting_factor c "13".
- Melanocyte-inhibiting_factor casNumber "2002".
- Melanocyte-inhibiting_factor excretion "N/A".
- Melanocyte-inhibiting_factor h "24".
- Melanocyte-inhibiting_factor hasPhotoCollection Melanocyte-inhibiting_factor.
- Melanocyte-inhibiting_factor iupacName "-N-pyrrolidine-2-carboxamide".
- Melanocyte-inhibiting_factor medlineplus "a605038".
- Melanocyte-inhibiting_factor metabolism "plasma protease enzymes".
- Melanocyte-inhibiting_factor molecularWeight "284.355".
- Melanocyte-inhibiting_factor n "4".
- Melanocyte-inhibiting_factor o "3".
- Melanocyte-inhibiting_factor pubchem "3896043".
- Melanocyte-inhibiting_factor routesOfAdministration "IV".
- Melanocyte-inhibiting_factor smiles "NC=O".
- Melanocyte-inhibiting_factor synonyms "L-propyl-L-leucyl-glycinamide".
- Melanocyte-inhibiting_factor verifiedrevid "436643072".
- Melanocyte-inhibiting_factor watchedfields "changed".
- Melanocyte-inhibiting_factor width "240".
- Melanocyte-inhibiting_factor subject Category:Peptides.
- Melanocyte-inhibiting_factor type Abstraction100002137.
- Melanocyte-inhibiting_factor type Amide114724264.
- Melanocyte-inhibiting_factor type Chemical114806838.
- Melanocyte-inhibiting_factor type Compound114818238.
- Melanocyte-inhibiting_factor type Material114580897.
- Melanocyte-inhibiting_factor type Matter100020827.
- Melanocyte-inhibiting_factor type OrganicCompound114727670.
- Melanocyte-inhibiting_factor type Part113809207.
- Melanocyte-inhibiting_factor type Peptide114743046.
- Melanocyte-inhibiting_factor type Peptides.
- Melanocyte-inhibiting_factor type PhysicalEntity100001930.
- Melanocyte-inhibiting_factor type Relation100031921.
- Melanocyte-inhibiting_factor type Substance100019613.
- Melanocyte-inhibiting_factor type Drug.
- Melanocyte-inhibiting_factor type FunctionalSubstance.
- Melanocyte-inhibiting_factor comment "Melanocyte-inhibiting factor (also known as Pro-Leu-Gly-NH2, Melanostatin, MSH release-inhibiting hormone or MIF-1) is an endogenous peptide fragment derived from cleavage of the hormone oxytocin, but having generally different actions in the body.".
- Melanocyte-inhibiting_factor label "Melanocyte-inhibiting factor".
- Melanocyte-inhibiting_factor label "Melanostatyna".
- Melanocyte-inhibiting_factor sameAs Melanostatyna.
- Melanocyte-inhibiting_factor sameAs m.0gx_gvx.
- Melanocyte-inhibiting_factor sameAs Q6811443.
- Melanocyte-inhibiting_factor sameAs Q6811443.
- Melanocyte-inhibiting_factor sameAs Melanocyte-inhibiting_factor.
- Melanocyte-inhibiting_factor wasDerivedFrom Melanocyte-inhibiting_factor?oldid=592468704.
- Melanocyte-inhibiting_factor depiction MIF-1_structure.png.
- Melanocyte-inhibiting_factor isPrimaryTopicOf Melanocyte-inhibiting_factor.