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- Imiglucerase abstract "Imiglucerase is a medication used in the treatment of Gaucher's disease.It is a recombinant DNA-produced analogue of human β-glucocerebrosidase.Cerezyme is a freeze-dried medicine containing imiglucerase, manufactured by Genzyme Corporation. It is givenintravenously after reconstitution as a treatment for Type 1 Gaucher's disease. It is available in formulations containing 200 or 400 units per vial. The specific activity of highly purified human enzyme is 890,000 units/mg. A typical dose is 2.5U/kg every two weeks, up to a maximum of 60 U/kg once every two weeks, and safety has been established from ages 2 and up. It is one of the most expensive drugs sold, with an annual cost to U.S. patients of $200,000. Due to the low profitability (and high expense) of developing medications for rare conditions, imiglucerase has been granted orphan drug status in the USA, Australia, and Japan.Cerezyme was one of the drugs manufactured at Genzyme's Allston, Massachusetts plant, for which production was disrupted in 2009 after contamination with Vesivirus 2117.".
- Imiglucerase atcPrefix "A16".
- Imiglucerase atcSuffix "AB02".
- Imiglucerase casNumber "143003-46-7".
- Imiglucerase drugbank "DB00053".
- Imiglucerase fdaUniiCode "Q6U6J48BWY".
- Imiglucerase iupacName "Human Beta-glucocerebrosidase".
- Imiglucerase wikiPageID "4156419".
- Imiglucerase wikiPageRevisionID "591776072".
- Imiglucerase atcPrefix "A16".
- Imiglucerase atcSuffix "AB02".
- Imiglucerase c "2532".
- Imiglucerase casNumber "143003".
- Imiglucerase chembl "1201632".
- Imiglucerase chemspiderid "NA".
- Imiglucerase drugbank "DB00053".
- Imiglucerase eliminationHalfLife "-624.0".
- Imiglucerase h "3854".
- Imiglucerase hasPhotoCollection Imiglucerase.
- Imiglucerase iupacName "Human Beta-glucocerebrosidase".
- Imiglucerase kegg "D02810".
- Imiglucerase licenceEu "Cerezyme".
- Imiglucerase licenceUs "Imiglucerase".
- Imiglucerase medlineplus "a601149".
- Imiglucerase molecularWeight "55597.4".
- Imiglucerase n "672".
- Imiglucerase o "711".
- Imiglucerase routesOfAdministration "Intravenous".
- Imiglucerase s "16".
- Imiglucerase unii "Q6U6J48BWY".
- Imiglucerase verifiedfields "changed".
- Imiglucerase verifiedrevid "458273717".
- Imiglucerase subject Category:Drugs_acting_on_the_gastrointestinal_system_and_metabolism.
- Imiglucerase subject Category:Orphan_drugs.
- Imiglucerase type Agent114778436.
- Imiglucerase type CausalAgent100007347.
- Imiglucerase type Drug103247620.
- Imiglucerase type DrugsActingOnTheGastrointestinalSystemAndMetabolism.
- Imiglucerase type Matter100020827.
- Imiglucerase type PhysicalEntity100001930.
- Imiglucerase type Substance100020090.
- Imiglucerase type Drug.
- Imiglucerase type DrugProduct.
- Imiglucerase type FunctionalSubstance.
- Imiglucerase comment "Imiglucerase is a medication used in the treatment of Gaucher's disease.It is a recombinant DNA-produced analogue of human β-glucocerebrosidase.Cerezyme is a freeze-dried medicine containing imiglucerase, manufactured by Genzyme Corporation. It is givenintravenously after reconstitution as a treatment for Type 1 Gaucher's disease. It is available in formulations containing 200 or 400 units per vial. The specific activity of highly purified human enzyme is 890,000 units/mg.".
- Imiglucerase label "Imiglucerase".
- Imiglucerase label "Imiglucerase".
- Imiglucerase label "Имиглуцераза".
- Imiglucerase label "セレザイム".
- Imiglucerase sameAs セレザイム.
- Imiglucerase sameAs Imiglucerase.
- Imiglucerase sameAs m.0bm4y1.
- Imiglucerase sameAs Q2620206.
- Imiglucerase sameAs Q2620206.
- Imiglucerase sameAs imiglucerase.
- Imiglucerase sameAs DB00053.
- Imiglucerase sameAs Imiglucerase.
- Imiglucerase wasDerivedFrom Imiglucerase?oldid=591776072.
- Imiglucerase isPrimaryTopicOf Imiglucerase.