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- Hydromorphone abstract "Hydromorphone, a more common synonym for dihydromorphinone (not to be confused by dihydromorphine, which is a different derivative of the morphine family), commonly a hydrochloride (brand names Palladone, Dilaudid, and numerous others) is a very potent centrally acting analgesic drug of the opioid class. It is a derivative of morphine; to be specific, a hydrogenated ketone thereof, and it can be said that hydromorphone is to morphine as hydrocodone is to codeine and, therefore, a semi-synthetic drug. It is in medical terms an opioid analgesic and in legal terms a narcotic. Hydromorphone is commonly used in the hospital setting, mostly intravenously (IV) because its bioavailability orally, rectally, and intranasally is very low. Sublingual administration is usually superior to swallowing for bioavailability and effects.Hydromorphone is much more soluble in water than morphine and therefore hydromorphone solutions can be produced to deliver the drug in a smaller volume of water. The hydrochloride salt is soluble in three parts of water whereas a gram of morphine hydrochloride dissolves in 16 ml of water; for all common purposes the pure powder for hospital use can be used to produce solutions of virtually arbitrary concentration. When the powder has appeared on the street, this very small volume of powder needed for a dose means that overdoses are likely for those who mistake it for heroin or other powdered narcotics, especially those that have been cut or stepped on already.Very small quantities of hydromorphone are detected in assays of opium on rare occasions; it appears to be produced by the plant under circumstances and by processes which are not understood at this time and may include the action of bacteria. A similar process and/or other metabolic processes in the plant may very well be responsible for the very low quantities of hydrocodone also found on rare occasions in opium and alkaloid mixtures derived therefrom; dihydrocodeine, oxymorphol, oxycodone, oxymorphone, metopon and possibly other derivatives of morphine and/or hydromorphone also are found in trace amounts in opium.".
- Hydromorphone atcPrefix "N02".
- Hydromorphone atcSuffix "AA03".
- Hydromorphone bioavailability "35.0".
- Hydromorphone bioavailability "58.0".
- Hydromorphone casNumber "466-99-9".
- Hydromorphone chEBI "5790".
- Hydromorphone drugbank "DB00327".
- Hydromorphone fdaUniiCode "Q812464R06".
- Hydromorphone iupacName "4,5-α-epoxy-3-hydroxy-17-methyl morphinan-6-one".
- Hydromorphone pubchem "5284570".
- Hydromorphone thumbnail Hydromorphone_-_Hydromorphon.svg?width=300.
- Hydromorphone wikiPageExternalLink exalgo-hydromorphone-hydrochloride-tablets-8-mg-12-mg-and-16-mg.
- Hydromorphone wikiPageExternalLink hydromorphone.htm.
- Hydromorphone wikiPageExternalLink hydromorphone.html.
- Hydromorphone wikiPageExternalLink dihydromorphinones.html.
- Hydromorphone wikiPageExternalLink 17pain-t.html.
- Hydromorphone wikiPageExternalLink www.paincare.ca.
- Hydromorphone wikiPageExternalLink 109026.
- Hydromorphone wikiPageID "317921".
- Hydromorphone wikiPageRevisionID "604439605".
- Hydromorphone atcPrefix "N02".
- Hydromorphone atcSuffix "AA03".
- Hydromorphone bioavailability "Oral: 30–35%, Intranasal: 52–58%".
- Hydromorphone brandName "Dilaudid".
- Hydromorphone c "17".
- Hydromorphone casNumber "466".
- Hydromorphone chebi "5790".
- Hydromorphone chembl "398707".
- Hydromorphone chemspiderid "4447624".
- Hydromorphone direction "vertical".
- Hydromorphone drugbank "DB00327".
- Hydromorphone eliminationHalfLife "10800.0".
- Hydromorphone excretion "Renal".
- Hydromorphone h "19".
- Hydromorphone hasPhotoCollection Hydromorphone.
- Hydromorphone image "Hydromorphone.JPG".
- Hydromorphone image "Hydromorphone_27feb.gif".
- Hydromorphone image "hydromorphone dilaudid.jpg".
- Hydromorphone inchi "1".
- Hydromorphone iupacName "45".
- Hydromorphone kegg "D08047".
- Hydromorphone legalAu "S8".
- Hydromorphone legalStatus "Class A—Non-Clinical use—and Schedule II—Clinical use ,".
- Hydromorphone legalStatus "DEA Schedule II".
- Hydromorphone medlineplus "a682013".
- Hydromorphone metabolism "Hepatic".
- Hydromorphone molecularWeight "321.8".
- Hydromorphone n "1".
- Hydromorphone o "3".
- Hydromorphone pregnancyCategory "C".
- Hydromorphone proteinBound "20.0".
- Hydromorphone pubchem "5284570".
- Hydromorphone routesOfAdministration "oral, intramuscular, intravenous, subcutaneous, intranasal, rectal, sublingual, transmucosal, buccal, transdermal".
- Hydromorphone smiles "O=C4[C@@H]5Oc1c2cC[C@H]3NC".
- Hydromorphone solubility "HCl: 333".
- Hydromorphone stdinchi "1".
- Hydromorphone stdinchikey "WVLOADHCBXTIJK-YNHQPCIGSA-N".
- Hydromorphone synonyms "dihydromorphinone".
- Hydromorphone unii "Q812464R06".
- Hydromorphone verifiedrevid "464191262".
- Hydromorphone width "180".
- Hydromorphone subject Category:Addictive_drugs.
- Hydromorphone subject Category:Euphoriants.
- Hydromorphone subject Category:German_inventions.
- Hydromorphone subject Category:Ketones.
- Hydromorphone subject Category:Morphinans.
- Hydromorphone subject Category:Mu-opioid_agonists.
- Hydromorphone subject Category:Phenols.
- Hydromorphone subject Category:Semisynthetic_opioids.
- Hydromorphone type Drug.
- Hydromorphone type DrugProduct.
- Hydromorphone type FunctionalSubstance.
- Hydromorphone comment "Hydromorphone, a more common synonym for dihydromorphinone (not to be confused by dihydromorphine, which is a different derivative of the morphine family), commonly a hydrochloride (brand names Palladone, Dilaudid, and numerous others) is a very potent centrally acting analgesic drug of the opioid class.".
- Hydromorphone label "Hidromorfona".
- Hydromorphone label "Hydromorfon".
- Hydromorphone label "Hydromorfon".
- Hydromorphone label "Hydromorphon".
- Hydromorphone label "Hydromorphone".
- Hydromorphone label "Hydromorphone".
- Hydromorphone label "Idromorfone".
- Hydromorphone label "Гидроморфон".
- Hydromorphone label "هيدرومورفين".
- Hydromorphone sameAs Hydromorfon.
- Hydromorphone sameAs Hydromorphon.
- Hydromorphone sameAs Hidromorfona.
- Hydromorphone sameAs Hydromorphone.
- Hydromorphone sameAs Idromorfone.
- Hydromorphone sameAs Hydromorfon.
- Hydromorphone sameAs Hydromorfon.
- Hydromorphone sameAs m.01v2_g.
- Hydromorphone sameAs Q303646.
- Hydromorphone sameAs Q303646.
- Hydromorphone sameAs Hydromorphone.
- Hydromorphone sameAs DB00327.
- Hydromorphone sameAs 3648.
- Hydromorphone wasDerivedFrom Hydromorphone?oldid=604439605.
- Hydromorphone depiction Hydromorphone_-_Hydromorphon.svg.
- Hydromorphone isPrimaryTopicOf Hydromorphone.