Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Histidine_kinase> ?p ?o }
Showing triples 1 to 48 of
48
with 100 triples per page.
- Histidine_kinase abstract "Histidine Kinases (HK) are multifunctional, typically transmembrane, proteins of the transferase class that play a role in signal transduction across the cellular membrane. The vast majority of HKs are homodimers that exhibit autokinase, phosphotransfer, and phosphatase activity. HKs can act as cellular receptors for signaling molecules in a way analogous to tyrosine kinase receptors (RTK). Multifunctional receptor molecules such as HKs and RTKs typically have portions on the outside of the cell (extracellular domain) that bind to hormone- or growth factor-like molecules, portions that span the cell membrane (transmembrane domain), and portions within the cell (intracellular domain) that contain the enzymatic activity. In addition to kinase activity, the intracellular domains typically have regions that bind to a secondary effector molecule or complex of molecules that further propagate signal transduction within the cell. Distinct from other classes of protein kinases, HKs are parts of a two-component signal transduction mechanisms. Described in greater detail below, essentially a HK transfers a phosphate group from ATP to a histidine residue within the kinase, and then to an aspartate residue on a 'receiver domain' on a different protein (or sometimes on the kinase itself) -- that aspartyl phosphate residue is thus activated for signaling.In terms of enzymology, a histidine kinase (EC 2.7.13.3, EnvZ, histidine protein kinase, protein histidine kinase, protein kinase (histidine), HK1, HP165, Sln1p) is an enzyme that catalyzes the chemical reactionATP + protein L-histidine ADP + protein N-phospho-L-histidine.Thus, the two substrates of this enzyme are ATP and protein L-histidine, whereas its two products are ADP and protein N-phospho-L-histidine.This type of enzyme is involved in signal transduction pathways upstream of many cellular processes including various metabolic, virulence, and homeostatic pathways.".
- Histidine_kinase ecNumber "2.7.13.3".
- Histidine_kinase thumbnail Hiskinase.jpg?width=300.
- Histidine_kinase wikiPageID "14678550".
- Histidine_kinase wikiPageRevisionID "591655391".
- Histidine_kinase caption "Crystallographic structure of ATP:protein-L-histidine N-phosphotransferase based on the coordinates.".
- Histidine_kinase casNumber "99283".
- Histidine_kinase ecNumber "2.7".
- Histidine_kinase goCode "4673".
- Histidine_kinase hasPhotoCollection Histidine_kinase.
- Histidine_kinase iubmbEcNumber "2".
- Histidine_kinase name "protein histidine kinase".
- Histidine_kinase subject Category:EC_2.7.13.
- Histidine_kinase subject Category:Enzymes_of_known_structure.
- Histidine_kinase type Abstraction100002137.
- Histidine_kinase type Activator114723079.
- Histidine_kinase type Catalyst114723628.
- Histidine_kinase type Chemical114806838.
- Histidine_kinase type Compound114818238.
- Histidine_kinase type Enzyme114732946.
- Histidine_kinase type EnzymesOfKnownStructure.
- Histidine_kinase type Macromolecule114944888.
- Histidine_kinase type Material114580897.
- Histidine_kinase type Matter100020827.
- Histidine_kinase type Molecule114682133.
- Histidine_kinase type OrganicCompound114727670.
- Histidine_kinase type Part113809207.
- Histidine_kinase type PhysicalEntity100001930.
- Histidine_kinase type Protein114728724.
- Histidine_kinase type Relation100031921.
- Histidine_kinase type Substance100019613.
- Histidine_kinase type Thing100002452.
- Histidine_kinase type Unit109465459.
- Histidine_kinase type Biomolecule.
- Histidine_kinase type Enzyme.
- Histidine_kinase type BiologicalObject.
- Histidine_kinase comment "Histidine Kinases (HK) are multifunctional, typically transmembrane, proteins of the transferase class that play a role in signal transduction across the cellular membrane. The vast majority of HKs are homodimers that exhibit autokinase, phosphotransfer, and phosphatase activity. HKs can act as cellular receptors for signaling molecules in a way analogous to tyrosine kinase receptors (RTK).".
- Histidine_kinase label "Histidine kinase".
- Histidine_kinase label "Histidinkinase".
- Histidine_kinase sameAs Histidinkinase.
- Histidine_kinase sameAs m.03gsv4g.
- Histidine_kinase sameAs Q1620721.
- Histidine_kinase sameAs Q1620721.
- Histidine_kinase sameAs Histidine_kinase.
- Histidine_kinase wasDerivedFrom Histidine_kinase?oldid=591655391.
- Histidine_kinase depiction Hiskinase.jpg.
- Histidine_kinase isPrimaryTopicOf Histidine_kinase.
- Histidine_kinase name "protein histidine kinase".