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- Argatroban abstract "Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor. In 2000, argatroban was licensed by the Food and Drug Administration (FDA) for prophylaxis or treatment of thrombosis in patients with heparin-induced thrombocytopenia (HIT). In 2002, it was approved for use during percutaneous coronary interventions in patients who have HIT or are at risk for developing it. In 2012, it was approved by the MHRA in the UK for anticoagulation in patients with Heparin-Induced Thrombocytopenia Type II (HIT) who require parenteral antithrombotic therapy.Argatroban is given intravenously and drug plasma concentrations reach steady state in 1-3 hours. Argatroban is metabolized in the liver and has a half-life of about 50 minutes. It is monitored by PTT. Because of its hepatic metabolism, it may be used in patients with renal dysfunction. (This is in contrast to lepirudin, a direct thrombin inhibitor that is primarily renally cleared).".
- Argatroban atcPrefix "B01".
- Argatroban atcSuffix "AE03".
- Argatroban bioavailability "100.0".
- Argatroban casNumber "74863-84-6".
- Argatroban drugbank "DB00278".
- Argatroban fdaUniiCode "OCY3U280Y3".
- Argatroban iupacName "(2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-".
- Argatroban iupacName "[[(3R)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]".
- Argatroban iupacName "carboxylic acid".
- Argatroban iupacName "sulfonylamino]pentanoyl]-4-methyl-piperidine-2-".
- Argatroban pubchem "440542".
- Argatroban thumbnail Argatroban.svg?width=300.
- Argatroban wikiPageExternalLink www.argatroban.com.
- Argatroban wikiPageID "2669812".
- Argatroban wikiPageRevisionID "576194142".
- Argatroban atcPrefix "B01".
- Argatroban atcSuffix "AE03".
- Argatroban bioavailability "100.0".
- Argatroban c "23".
- Argatroban casNumber "74863".
- Argatroban chembl "1166".
- Argatroban chemspiderid "389444".
- Argatroban drugbank "DB00278".
- Argatroban eliminationHalfLife "3060.0".
- Argatroban h "36".
- Argatroban hasPhotoCollection Argatroban.
- Argatroban inchi "1".
- Argatroban inchikey "KXNPVXPOPUZYGB-VSVYTNTFBD".
- Argatroban iupacName "-1".
- Argatroban iupacName "[[-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]".
- Argatroban iupacName "carboxylic acid".
- Argatroban iupacName "sulfonylamino]pentanoyl]-4-methyl-piperidine-2-".
- Argatroban kegg "4931.0".
- Argatroban metabolism "hepatic".
- Argatroban molecularWeight "508.635".
- Argatroban n "6".
- Argatroban o "5".
- Argatroban proteinBound "54.0".
- Argatroban pubchem "440542".
- Argatroban routesOfAdministration "intravenous".
- Argatroban s "1".
- Argatroban smiles "O=C[C@@H]3NCC[C@@H]C3".
- Argatroban stdinchi "1".
- Argatroban stdinchikey "KXNPVXPOPUZYGB-IOVMHBDKSA-N".
- Argatroban tradename "Argatroban".
- Argatroban unii "OCY3U280Y3".
- Argatroban verifiedfields "changed".
- Argatroban verifiedrevid "457140717".
- Argatroban subject Category:Direct_thrombin_inhibitors.
- Argatroban subject Category:Guanidines.
- Argatroban subject Category:Sulfonamides.
- Argatroban type Agent114778436.
- Argatroban type Antibacterial102716205.
- Argatroban type CausalAgent100007347.
- Argatroban type DirectThrombinInhibitors.
- Argatroban type Drug103247620.
- Argatroban type Inhibitor114724436.
- Argatroban type Matter100020827.
- Argatroban type Medicine103740161.
- Argatroban type PhysicalEntity100001930.
- Argatroban type Substance100020090.
- Argatroban type SulfaDrug104352070.
- Argatroban type Sulfonamides.
- Argatroban type Drug.
- Argatroban type DrugProduct.
- Argatroban type FunctionalSubstance.
- Argatroban comment "Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor. In 2000, argatroban was licensed by the Food and Drug Administration (FDA) for prophylaxis or treatment of thrombosis in patients with heparin-induced thrombocytopenia (HIT). In 2002, it was approved for use during percutaneous coronary interventions in patients who have HIT or are at risk for developing it.".
- Argatroban label "Argatroban".
- Argatroban label "Argatroban".
- Argatroban label "Argatroban".
- Argatroban label "Argatrobana".
- Argatroban sameAs Argatroban.
- Argatroban sameAs Argatroban.
- Argatroban sameAs Argatrobana.
- Argatroban sameAs m.07wrx6.
- Argatroban sameAs Q474880.
- Argatroban sameAs Q474880.
- Argatroban sameAs DB00278.
- Argatroban sameAs Argatroban.
- Argatroban wasDerivedFrom Argatroban?oldid=576194142.
- Argatroban depiction Argatroban.svg.
- Argatroban isPrimaryTopicOf Argatroban.