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- Aprotinin abstract "The drug aprotinin (Trasylol, previously Bayer and now Nordic Group pharmaceuticals), is the small protein bovine pancreatic trypsin inhibitor, or BPTI, which inhibits trypsin and related proteolytic enzymes. Under the trade name Trasylol, aprotinin was used as a medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. Its main effect is the slowing down of fibrinolysis, the process that leads to the breakdown of blood clots. The aim in its use was to decrease the need for blood transfusions during surgery, as well as end-organ damage due to hypotension (low blood pressure) as a result of marked blood loss. The drug was temporarily withdrawn worldwide in 2007 after studies suggested that its use increased the risk of complications or death; this was confirmed by follow-up studies. Trasylol sales were suspended in May 2008, except for very restricted research use. In February 2012 the European Medicines Agency (EMA) scientific committee reverted its previous standpoint regarding aprotinin, and has recommended that the suspension be lifted. Nordic became distributor of aprotinin in 2012.".
- Aprotinin atcPrefix "B02".
- Aprotinin atcSuffix "AB01".
- Aprotinin bioavailability "100.0".
- Aprotinin casNumber "9087-70-1".
- Aprotinin drugbank "DB06692".
- Aprotinin fdaUniiCode "04XPW8C0FL".
- Aprotinin iupacName "Aprotinin".
- Aprotinin thumbnail Aprotinin.png?width=300.
- Aprotinin wikiPageExternalLink merops.cgi?id=I02.001.
- Aprotinin wikiPageExternalLink searchResults.html?display=both&term=P00974.
- Aprotinin wikiPageID "4628609".
- Aprotinin wikiPageRevisionID "598606698".
- Aprotinin atcPrefix "B02".
- Aprotinin atcSuffix "AB01".
- Aprotinin bioavailability "100.0".
- Aprotinin c "284".
- Aprotinin caption "BPTI sequence, with its folded 3D structure represented by a ribbon for the secondary structure and a stick model for the backbone and sidechains.".
- Aprotinin casNumber "9087".
- Aprotinin chembl "1201619".
- Aprotinin chemspiderid "NA".
- Aprotinin chromosome "13".
- Aprotinin dependencyLiability "None".
- Aprotinin drugbank "DB06692".
- Aprotinin entrezchromosome "NC_007311".
- Aprotinin entrezgene "404172".
- Aprotinin genlocEnd "75030832".
- Aprotinin genlocStart "75024552".
- Aprotinin h "432".
- Aprotinin hasPhotoCollection Aprotinin.
- Aprotinin iupacName "Aprotinin".
- Aprotinin kegg "D02971".
- Aprotinin legalStatus "RX/POM".
- Aprotinin molecularWeight "6511.51".
- Aprotinin n "84".
- Aprotinin name "Pancreatic trypsin inhibitor".
- Aprotinin o "79".
- Aprotinin organism "Bos taurus".
- Aprotinin pdb "4".
- Aprotinin pdbSupplemental searchResults.html?display=both&term=P00974.
- Aprotinin pregnancyCategory "X".
- Aprotinin refseqmrna "NM_001001554".
- Aprotinin refseqprotein "NP_001001554".
- Aprotinin routesOfAdministration "Intravenous".
- Aprotinin s "7".
- Aprotinin symbol "PTI".
- Aprotinin synonyms "Trasylol, bovine pancreatic trypsin inhibitor".
- Aprotinin taxid "9913".
- Aprotinin unii "4".
- Aprotinin uniprot "P00974".
- Aprotinin verifiedfields "changed".
- Aprotinin verifiedrevid "477350259".
- Aprotinin width "181".
- Aprotinin subject Category:Antifibrinolytics.
- Aprotinin subject Category:Proteins.
- Aprotinin type Abstraction100002137.
- Aprotinin type Chemical114806838.
- Aprotinin type Compound114818238.
- Aprotinin type Macromolecule114944888.
- Aprotinin type Material114580897.
- Aprotinin type Matter100020827.
- Aprotinin type Molecule114682133.
- Aprotinin type OrganicCompound114727670.
- Aprotinin type Part113809207.
- Aprotinin type PhysicalEntity100001930.
- Aprotinin type Protein114728724.
- Aprotinin type Proteins.
- Aprotinin type Relation100031921.
- Aprotinin type Substance100019613.
- Aprotinin type Thing100002452.
- Aprotinin type Unit109465459.
- Aprotinin type Drug.
- Aprotinin type DrugProduct.
- Aprotinin type FunctionalSubstance.
- Aprotinin comment "The drug aprotinin (Trasylol, previously Bayer and now Nordic Group pharmaceuticals), is the small protein bovine pancreatic trypsin inhibitor, or BPTI, which inhibits trypsin and related proteolytic enzymes. Under the trade name Trasylol, aprotinin was used as a medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. Its main effect is the slowing down of fibrinolysis, the process that leads to the breakdown of blood clots.".
- Aprotinin label "Aprotinin".
- Aprotinin label "Aprotinin".
- Aprotinin label "Aprotinina".
- Aprotinin label "Aprotinina".
- Aprotinin label "Aprotynina".
- Aprotinin label "Апротинин".
- Aprotinin sameAs Aprotinin.
- Aprotinin sameAs Aprotinina.
- Aprotinin sameAs Aprotinina.
- Aprotinin sameAs Aprotynina.
- Aprotinin sameAs m.0cdfym.
- Aprotinin sameAs Q418625.
- Aprotinin sameAs Q418625.
- Aprotinin sameAs Aprotinin.
- Aprotinin wasDerivedFrom Aprotinin?oldid=598606698.
- Aprotinin depiction Aprotinin.png.
- Aprotinin isPrimaryTopicOf Aprotinin.