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DBpedia 2016-04

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Matches in DBpedia 2016-04 for { ?s ?p "This is a list of cocaine analogues. A cocaine analogue retains 3β-benzoyloxy or similar functionality (the term specifically used usually distinguishes from phenyltropanes, but generally as a category includes them) on a tropane skeleton. As compared to other stimulants of the kind. Many of the semi-synthetic cocaine analogues proper which have been made & studied have consisted of among the nine following classes of compounds: stereoisomers of cocaine 3β-phenyl ring substituted analogues 2β-substituted analogues N-modified analogues of cocaine 3β-carbamoyl analogues 3β-alkyl-3-benzyl tropanes 6/7-substituted cocaines 6-alkyl-3-benzyl tropanes piperidine homologues of cocaineHowever strict analogues of cocaine would also include such other potential combinations as phenacyltropanes & other carbon branched replacements not listed above. The term may also be loosely used to refer to drugs manufactured from cocaine or having their basis as a total synthesis of cocaine, but modified to alter their effect & QSAR. These include both intracellular sodium channel blocker anesthetics and stimulant dopamine reuptake inhibitor ligands (such as certain, namely tropane-bridged-excised, piperidines). Additionally, researchers have supported combinatorial approaches for taking the most promising analogues currently elucidated and mixing them to the end of discovering novel & efficacious compounds to optimize their utilization for differing distinct specified purposes."@en }

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