Matches in DBpedia 2016-04 for { ?s ?p "Genome editing, or genome editing with engineered nucleases (GEEN) is a type of genetic engineering in which DNA is inserted, deleted or replaced in the genome of an organism using engineered nucleases, or \"molecular scissors.\" These nucleases create site-specific double-strand breaks (DSBs) at desired locations in the genome. The induced double-strand breaks are repaired through nonhomologous end-joining (NHEJ) or homologous recombination (HR), resulting in targeted mutations ('edits').There are currently four families of engineered nucleases being used: Meganucleases, Zinc finger nucleases (ZFNs), Transcription Activator-Like Effector-based Nucleases (TALEN®), and the CRISPR-Cas system.Genome editing was selected by Nature Methods as the 2011 Method of the Year. The CRISPR-Cas system was selected by Science Magazine as 2015 Breakthrough of the Year"@en }
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- Genome_editing abstract "Genome editing, or genome editing with engineered nucleases (GEEN) is a type of genetic engineering in which DNA is inserted, deleted or replaced in the genome of an organism using engineered nucleases, or \"molecular scissors.\" These nucleases create site-specific double-strand breaks (DSBs) at desired locations in the genome. The induced double-strand breaks are repaired through nonhomologous end-joining (NHEJ) or homologous recombination (HR), resulting in targeted mutations ('edits').There are currently four families of engineered nucleases being used: Meganucleases, Zinc finger nucleases (ZFNs), Transcription Activator-Like Effector-based Nucleases (TALEN®), and the CRISPR-Cas system.Genome editing was selected by Nature Methods as the 2011 Method of the Year. The CRISPR-Cas system was selected by Science Magazine as 2015 Breakthrough of the Year".