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DBpedia 2016-04

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Matches in DBpedia 2016-04 for { ?s ?p "Genetic purging is the reduction of the frequency of a deleterious allele occurred by an increased efficiency of natural selection that is prompted by inbreeding.Purging occurs because many deleterious alleles only express all their harmful effect in homozygosis. During inbreeding, as related individuals mate, they produce offspring that are more likely to be homozygous, so that these deleterious alleles appear more often in homozygous individuals that are less fit and that pass fewer copies of their genes to future generations. This allows natural selection to purge the deleterious alleles.Purging reduces both the overall number of recessive deleterious alleles and the decline of mean fitness caused by inbreeding (the inbreeding depression for fitness). The term “purge” is sometimes used for selection against deleterious alleles in a general way. It would avoid ambiguity to use “purifying selection” in that general context, and to reserve purging to its more strict meaning defined above.The mechanism of purging and its main consequences are explained below in more detail."@en }

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