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DBpedia 2016-04

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Matches in DBpedia 2016-04 for { ?s ?p "Alfred L. Wilds (Mar. 1 1915 - July 4, 2002) was a professor emeritus of chemistry at the University of Wisconsin in Madison. His doctoral research was done under the guidance of Professor Werner E. Bachman atMichigan at a time (mid thirties) when modern organic chemistry and synthesis was just starting toemerge. His thesis work is hailed even today as a major andrevolutionary break with the past. The total synthesis of the steroidalsex hormone Equilenin, published in the Journal of the AmericanChemical Society in 1940, was the first successful total synthesis of acomplex natural product. In the context of the time, it was not a widely disseminated view that chemical structures of this degree of structural and stereochemical complexity could indeed be made from common starting chemicals. The Vitalism theory still distorted many people's views as to the relationship between \"ordinary\" chemicals and such esoterica as animal-isolated sex hormones. So the \"Bachmann, Cole and Wilds\" paper is widely recognized as inaugurating the modern era of chemical synthesis of complex medicinally important structures. 70+ years later, synthesis of such complex targets as HIV protease inhibitors are as a result of the Equilenin synthesis by Al Wilds."@en }

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