Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Sonepiprazole> ?p ?o }
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- Sonepiprazole abstract "Sonepiprazole (U-101,387, PNU-101,387-G) is a drug of the phenylpiperazine class which acts as a highly selective D4 receptor antagonist. In animals, unlike D2 receptor antagonists like haloperidol, sonepiprazole does not block the behavioral effects of amphetamine or apomorphine, does not alter spontaneous locomotor activity on its own, and lacks extrapyramidal and neuroendocrine effects. However, it does reverse the prepulse inhibition deficits induced by apomorphine, and has also been shown to enhance cortical activity and inhibit stress-induced cognitive impairment. As a result, it was investigated as an antipsychotic for the treatment of schizophrenia in a placebo-controlled clinical trial, but in contrast to its comparator olanzapine no benefits were found and it was not researched further for this indication.".
- Sonepiprazole atcPrefix "none".
- Sonepiprazole casNumber "170858-34-1".
- Sonepiprazole fdaUniiCode "O609V24217".
- Sonepiprazole iupacName "4-(4-{2-[(1S)-3,4-dihydro-1H-isochromen-1-yl]ethyl}piperazin-1-yl)benzenesulfonamide".
- Sonepiprazole pubchem "133079".
- Sonepiprazole thumbnail Sonepiprazole.png?width=300.
- Sonepiprazole wikiPageID "27132570".
- Sonepiprazole wikiPageLength "4815".
- Sonepiprazole wikiPageOutDegree "26".
- Sonepiprazole wikiPageRevisionID "679085726".
- Sonepiprazole wikiPageWikiLink Amphetamine.
- Sonepiprazole wikiPageWikiLink Animal_locomotion.
- Sonepiprazole wikiPageWikiLink Antipsychotic.
- Sonepiprazole wikiPageWikiLink Apomorphine.
- Sonepiprazole wikiPageWikiLink Binding_selectivity.
- Sonepiprazole wikiPageWikiLink Category:Isochromenes.
- Sonepiprazole wikiPageWikiLink Category:Piperazines.
- Sonepiprazole wikiPageWikiLink Category:Sulfonamides.
- Sonepiprazole wikiPageWikiLink Cerebral_cortex.
- Sonepiprazole wikiPageWikiLink Clinical_trial.
- Sonepiprazole wikiPageWikiLink Cognition.
- Sonepiprazole wikiPageWikiLink Cognitive.
- Sonepiprazole wikiPageWikiLink D2_receptor.
- Sonepiprazole wikiPageWikiLink D4_receptor.
- Sonepiprazole wikiPageWikiLink Dopamine_receptor_D2.
- Sonepiprazole wikiPageWikiLink Dopamine_receptor_D4.
- Sonepiprazole wikiPageWikiLink Drug.
- Sonepiprazole wikiPageWikiLink Extrapyramidal_symptoms.
- Sonepiprazole wikiPageWikiLink Haloperidol.
- Sonepiprazole wikiPageWikiLink Locomotor_activity.
- Sonepiprazole wikiPageWikiLink Mouth.
- Sonepiprazole wikiPageWikiLink Neuroendocrine.
- Sonepiprazole wikiPageWikiLink Neuroendocrine_cell.
- Sonepiprazole wikiPageWikiLink Olanzapine.
- Sonepiprazole wikiPageWikiLink Phenylpiperazine.
- Sonepiprazole wikiPageWikiLink Placebo.
- Sonepiprazole wikiPageWikiLink Prepulse_inhibition.
- Sonepiprazole wikiPageWikiLink Receptor_antagonist.
- Sonepiprazole wikiPageWikiLink Schizophrenia.
- Sonepiprazole wikiPageWikiLink Stress_(biology).
- Sonepiprazole wikiPageWikiLinkText "Sonepiprazole".
- Sonepiprazole atcPrefix "none".
- Sonepiprazole c "21".
- Sonepiprazole casNumber "170858".
- Sonepiprazole chemspiderid "117441".
- Sonepiprazole h "27".
- Sonepiprazole hasPhotoCollection Sonepiprazole.
- Sonepiprazole iupacName "4".
- Sonepiprazole iupharLigand "980".
- Sonepiprazole legalStatus "Uncontrolled".
- Sonepiprazole molecularWeight "401.52".
- Sonepiprazole n "3".
- Sonepiprazole o "3".
- Sonepiprazole pubchem "133079".
- Sonepiprazole routesOfAdministration Mouth.
- Sonepiprazole s "1".
- Sonepiprazole smiles "O=Sc1cccN2CCNCC[C@@H]4OCCc3ccccc34".
- Sonepiprazole unii "O609V24217".
- Sonepiprazole wikiPageUsesTemplate Template:Dopaminergics.
- Sonepiprazole wikiPageUsesTemplate Template:Drugbox.
- Sonepiprazole wikiPageUsesTemplate Template:Nootropics.
- Sonepiprazole wikiPageUsesTemplate Template:Piperazines.
- Sonepiprazole wikiPageUsesTemplate Template:Reflist.
- Sonepiprazole subject Category:Isochromenes.
- Sonepiprazole subject Category:Piperazines.
- Sonepiprazole subject Category:Sulfonamides.
- Sonepiprazole hypernym Drug.
- Sonepiprazole type ChemicalSubstance.
- Sonepiprazole type Drug.
- Sonepiprazole type Amide.
- Sonepiprazole type Drug.
- Sonepiprazole type Heterocycle.
- Sonepiprazole type Sulfonamide.
- Sonepiprazole type ChemicalObject.
- Sonepiprazole type Thing.
- Sonepiprazole type Q8386.
- Sonepiprazole comment "Sonepiprazole (U-101,387, PNU-101,387-G) is a drug of the phenylpiperazine class which acts as a highly selective D4 receptor antagonist. In animals, unlike D2 receptor antagonists like haloperidol, sonepiprazole does not block the behavioral effects of amphetamine or apomorphine, does not alter spontaneous locomotor activity on its own, and lacks extrapyramidal and neuroendocrine effects.".
- Sonepiprazole label "Sonepiprazole".
- Sonepiprazole sameAs m.0bwk5h8.
- Sonepiprazole sameAs Sonepiprazol.
- Sonepiprazole sameAs Sonepiprazol.
- Sonepiprazole sameAs Q7560929.
- Sonepiprazole sameAs Q7560929.
- Sonepiprazole wasDerivedFrom Sonepiprazole?oldid=679085726.
- Sonepiprazole depiction Sonepiprazole.png.
- Sonepiprazole isPrimaryTopicOf Sonepiprazole.
