Matches in DBpedia 2015-10 for { ?s ?p "This gene encodes a member of the basic helix-loop-helix family of transcription factors. The protein activates transcription by binding to the E box . Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. It is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers. The presence of a CAG repeat in the gene suggests that it may also play a role in tumor formation."@en }
Showing triples 1 to 1 of
1
with 100 triples per page.
- ASCL1 summaryText "This gene encodes a member of the basic helix-loop-helix family of transcription factors. The protein activates transcription by binding to the E box . Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. It is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers. The presence of a CAG repeat in the gene suggests that it may also play a role in tumor formation.".