Matches in DBpedia 2015-10 for { ?s ?p "The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon , this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 , in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus."@en }
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- STAT2 summaryText "The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon , this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 , in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.".