Matches in DBpedia 2015-10 for { ?s ?p "The Structural Classification of Proteins (SCOP) database is a largely manual classification of protein structural domains based on similarities of their structures and amino acid sequences. A motivation for this classification is to determine the evolutionary relationship between proteins. Proteins with the same shapes but having little sequence or functional similarity are placed in different superfamilies, and are assumed to have only a very distant common ancestor. Proteins having the same shape and some similarity of sequence and/or function are placed in "families", and are assumed to have a closer common ancestor.The SCOP database is freely accessible on the internet. SCOP was created in 1994 in the Centre for Protein Engineering and the Laboratory of Molecular Biology. It was maintained by Alexey G. Murzin and his colleagues in the Centre for Protein Engineering until its closure in 2010 and subsequently at the Laboratory of Molecular Biology in Cambridge, England. As of January 2014, the work on SCOP has been discontinued and the last official version of SCOP is 1.75 (released June 2009). The prototype of a new Structural Classification of Proteins 2 (SCOP2) database has been made publicly available. SCOP2 defines a new approach to the classification of proteins that is essentially different from SCOP, but retains its best features."@en }
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- Structural_Classification_of_Proteins_database abstract "The Structural Classification of Proteins (SCOP) database is a largely manual classification of protein structural domains based on similarities of their structures and amino acid sequences. A motivation for this classification is to determine the evolutionary relationship between proteins. Proteins with the same shapes but having little sequence or functional similarity are placed in different superfamilies, and are assumed to have only a very distant common ancestor. Proteins having the same shape and some similarity of sequence and/or function are placed in "families", and are assumed to have a closer common ancestor.The SCOP database is freely accessible on the internet. SCOP was created in 1994 in the Centre for Protein Engineering and the Laboratory of Molecular Biology. It was maintained by Alexey G. Murzin and his colleagues in the Centre for Protein Engineering until its closure in 2010 and subsequently at the Laboratory of Molecular Biology in Cambridge, England. As of January 2014, the work on SCOP has been discontinued and the last official version of SCOP is 1.75 (released June 2009). The prototype of a new Structural Classification of Proteins 2 (SCOP2) database has been made publicly available. SCOP2 defines a new approach to the classification of proteins that is essentially different from SCOP, but retains its best features.".