Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q704923> ?p ?o }
Showing triples 1 to 49 of
49
with 100 triples per page.
- Q704923 subject Q6994655.
- Q704923 subject Q7279730.
- Q704923 subject Q7426015.
- Q704923 subject Q8638136.
- Q704923 subject Q8707756.
- Q704923 subject Q9019802.
- Q704923 abstract "Molybdenum cofactor (Moco) is a metal-containing Prosthetic group common to nearly all molybdoenzymes and is ubiquitous to all kingdoms of life. Moco-dependent enzymes play central roles in many biologically important processes such as purine and sulfur catabolism in mammals, anaerobic respiration in bacteria, and nitrate assimilation in plants. In humans, Moco deficiency results in the pleiotropic loss of activity of enzymes such as sulfite oxidase, xanthine oxidoreductase, and aldehyde oxidase, which in turn causes neurological abnormalities and early childhood death.It is a coordination complex formed between molybdopterin (which, despite the name, does not contain molybdenum) and an oxide of molybdenum. The molybdenum in this cofactor is in its fully oxidized state (VI), similar to molybdenum in molybdate ion.Unlike many other cofactors, Moco cannot be taken up as a nutrient, and thus requires de novo biosynthesis. Molybdenum cofactor biosynthesis occurs in four steps: (i) the radical-mediated cyclization of nucleotide, guanosine triphosphate (GTP), to (8S)‑3 ́,8‐cyclo‑7,8‑dihydroguanosine 5 ́‑triphosphate (3 ́,8‑cH2GTP), (ii) the formation of cyclic pyranopterin monophosphate (cPMP) from the 3 ́,8‑cH2GTP, (iii) the conversion of cPMP into molybdopterin (MPT), (iv) the insertion of molybdate into MPT to form Moco.Molybdenum cofactor functions directly in ethylbenzene dehydrogenase, glyceraldehyde-3-phosphate ferredoxin oxidoreductase, and respiratory arsenate reductaseIn animals and plants these enzymes use molybdenum bound at the active site in a tricyclic molybdenum cofactor. All molybdenum-using enzymes so far identified in nature use this cofactor, save for the phylogenetically ancient molybdenum nitrogenases, which fix nitrogen in some bacteria and cyanobacteria. Molybdenum enzymes in plants and animals catalyze the oxidation and sometimes reduction of certain small molecules, as part of the regulation of nitrogen, sulfur and carbon cycles.".
- Q704923 thumbnail Molybdenum_cofactor.svg?width=300.
- Q704923 wikiPageWikiLink Q1053.
- Q704923 wikiPageWikiLink Q1063702.
- Q704923 wikiPageWikiLink Q1361502.
- Q704923 wikiPageWikiLink Q14916244.
- Q704923 wikiPageWikiLink Q1621463.
- Q704923 wikiPageWikiLink Q167751.
- Q704923 wikiPageWikiLink Q18029242.
- Q704923 wikiPageWikiLink Q18029245.
- Q704923 wikiPageWikiLink Q18035156.
- Q704923 wikiPageWikiLink Q18038772.
- Q704923 wikiPageWikiLink Q18041493.
- Q704923 wikiPageWikiLink Q238156.
- Q704923 wikiPageWikiLink Q3009384.
- Q704923 wikiPageWikiLink Q3273039.
- Q704923 wikiPageWikiLink Q3623960.
- Q704923 wikiPageWikiLink Q3733789.
- Q704923 wikiPageWikiLink Q392227.
- Q704923 wikiPageWikiLink Q407280.
- Q704923 wikiPageWikiLink Q409526.
- Q704923 wikiPageWikiLink Q410381.
- Q704923 wikiPageWikiLink Q412509.
- Q704923 wikiPageWikiLink Q50690.
- Q704923 wikiPageWikiLink Q5198226.
- Q704923 wikiPageWikiLink Q619698.
- Q704923 wikiPageWikiLink Q6994655.
- Q704923 wikiPageWikiLink Q7279730.
- Q704923 wikiPageWikiLink Q7426015.
- Q704923 wikiPageWikiLink Q8047.
- Q704923 wikiPageWikiLink Q82551.
- Q704923 wikiPageWikiLink Q8638136.
- Q704923 wikiPageWikiLink Q8707756.
- Q704923 wikiPageWikiLink Q9019802.
- Q704923 wikiPageWikiLink Q93315.
- Q704923 type ChemicalCompound.
- Q704923 type ChemicalSubstance.
- Q704923 type ChemicalObject.
- Q704923 type Thing.
- Q704923 type Q11173.
- Q704923 comment "Molybdenum cofactor (Moco) is a metal-containing Prosthetic group common to nearly all molybdoenzymes and is ubiquitous to all kingdoms of life. Moco-dependent enzymes play central roles in many biologically important processes such as purine and sulfur catabolism in mammals, anaerobic respiration in bacteria, and nitrate assimilation in plants.".
- Q704923 label "Molybdenum cofactor".
- Q704923 depiction Molybdenum_cofactor.svg.