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- Q1175385 subject Q8529119.
- Q1175385 subject Q8788974.
- Q1175385 abstract "Mephenytoin (marketed as Mesantoin by Novartis) is a hydantoin, used as an anticonvulsant. It was introduced approximately 10 years after phenytoin, in the late 1940s. The significant metabolite of mephenytoin is nirvanol (5-ethyl-5-phenylhydantoin), which was the first hydantoin (briefly used as a hypnotic). However, nirvanol is quite toxic and mephenytoin was only considered after other less toxic anticonvulsants had failed. It can cause potentially fatal blood dyscrasia in 1% of patients.Mephenytoin is no longer available in the US or the UK. It is still studied largely because of its interesting hydroxylation polymorphism.".
- Q1175385 atcPrefix "N03".
- Q1175385 atcSuffix "AB04".
- Q1175385 casNumber "50-12-4".
- Q1175385 drugbank "DB00532".
- Q1175385 fdaUniiCode "R420KW629U".
- Q1175385 iupacName "5-ethyl-3-methyl-5-phenyl-imidazolidine-2,4-dione".
- Q1175385 pubchem "4060".
- Q1175385 thumbnail Mephenytoin.svg?width=300.
- Q1175385 wikiPageExternalLink detail.go?type=chem&acc=D008617.
- Q1175385 wikiPageWikiLink Q3709969.
- Q1175385 wikiPageWikiLink Q407595.
- Q1175385 wikiPageWikiLink Q410400.
- Q1175385 wikiPageWikiLink Q418082.
- Q1175385 wikiPageWikiLink Q485680.
- Q1175385 wikiPageWikiLink Q576618.
- Q1175385 wikiPageWikiLink Q62962.
- Q1175385 wikiPageWikiLink Q7040139.
- Q1175385 wikiPageWikiLink Q8529119.
- Q1175385 wikiPageWikiLink Q8788974.
- Q1175385 wikiPageWikiLink Q898497.
- Q1175385 atcPrefix "N03".
- Q1175385 atcSuffix "AB04".
- Q1175385 casNumber "50".
- Q1175385 drugbank "DB00532".
- Q1175385 iupacName "5".
- Q1175385 pubchem "4060".
- Q1175385 unii "R420KW629U".
- Q1175385 type ChemicalSubstance.
- Q1175385 type Drug.
- Q1175385 type ChemicalObject.
- Q1175385 type Thing.
- Q1175385 type Q8386.
- Q1175385 comment "Mephenytoin (marketed as Mesantoin by Novartis) is a hydantoin, used as an anticonvulsant. It was introduced approximately 10 years after phenytoin, in the late 1940s. The significant metabolite of mephenytoin is nirvanol (5-ethyl-5-phenylhydantoin), which was the first hydantoin (briefly used as a hypnotic). However, nirvanol is quite toxic and mephenytoin was only considered after other less toxic anticonvulsants had failed.".
- Q1175385 label "Mephenytoin".
- Q1175385 depiction Mephenytoin.svg.