Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/PHLPP> ?p ?o }
- PHLPP abstract "The PHLPP isoforms (PH domain and Leucine rich repeat Protein Phosphatases) are a pair of protein phosphatases, PHLPP1 and PHLPP2, that are important regulators of Akt serine-threonine kinases (Akt1, Akt2, Akt3) and conventional/novel protein kinase C (PKC) isoforms. PHLPP may act as a tumor suppressor in several types of cancer due to its ability to block growth factor-induced signaling in cancer cells.PHLPP dephosphorylates Ser-473 (the hydrophobic motif) in Akt, thus partially inactivating the kinase.In addition, PHLPP dephosphorylates conventional and novel members of the protein kinase C family at their hydrophobic motifs, corresponding to Ser-660 in PKCβII.".
- PHLPP arm "q".
- PHLPP band "21.32".
- PHLPP band "22.2".
- PHLPP chromosome "16".
- PHLPP chromosome "18".
- PHLPP ecNumber "3.1.3.16".
- PHLPP entrezgene "23035".
- PHLPP entrezgene "23239".
- PHLPP hgncid "20610".
- PHLPP hgncid "29149".
- PHLPP omim "609396".
- PHLPP omim "611066".
- PHLPP refseq "NM_015020".
- PHLPP refseq "XM_166290".
- PHLPP symbol "PHLPP".
- PHLPP symbol "PHLPP1, PLEKHE1".
- PHLPP symbol "PHLPP2".
- PHLPP symbol "PHLPPL".
- PHLPP uniprot "O60346".
- PHLPP uniprot "Q6ZVD8".
- PHLPP wikiPageID "10292285".
- PHLPP wikiPageLength "12002".
- PHLPP wikiPageOutDegree "48".
- PHLPP wikiPageRevisionID "701365768".
- PHLPP wikiPageWikiLink AKT1.
- PHLPP wikiPageWikiLink AKT2.
- PHLPP wikiPageWikiLink AKT3.
- PHLPP wikiPageWikiLink Apoptosis.
- PHLPP wikiPageWikiLink Category:EC_3.1.3.
- PHLPP wikiPageWikiLink Category:Signal_transduction.
- PHLPP wikiPageWikiLink Chronic_myelogenous_leukemia.
- PHLPP wikiPageWikiLink Diabetes_mellitus.
- PHLPP wikiPageWikiLink Diglyceride.
- PHLPP wikiPageWikiLink Enzyme.
- PHLPP wikiPageWikiLink G_protein–coupled_receptor.
- PHLPP wikiPageWikiLink Imatinib.
- PHLPP wikiPageWikiLink Insulin_receptor.
- PHLPP wikiPageWikiLink Insulin_resistance.
- PHLPP wikiPageWikiLink Leucine-rich_repeat.
- PHLPP wikiPageWikiLink Loss_of_heterozygosity.
- PHLPP wikiPageWikiLink Magnesium.
- PHLPP wikiPageWikiLink Manganese.
- PHLPP wikiPageWikiLink N-terminus.
- PHLPP wikiPageWikiLink Oncogene.
- PHLPP wikiPageWikiLink PDK2.
- PHLPP wikiPageWikiLink PDZ_domain.
- PHLPP wikiPageWikiLink PHLPPL.
- PHLPP wikiPageWikiLink PHLPP_(gene).
- PHLPP wikiPageWikiLink Philadelphia_chromosome.
- PHLPP wikiPageWikiLink Phosphatase.
- PHLPP wikiPageWikiLink Phosphatidylinositol_(3,4,5)-trisphosphate.
- PHLPP wikiPageWikiLink Phosphomimetics.
- PHLPP wikiPageWikiLink Pleckstrin_homology_domain.
- PHLPP wikiPageWikiLink Protein.
- PHLPP wikiPageWikiLink Protein_kinase.
- PHLPP wikiPageWikiLink Protein_kinase_B.
- PHLPP wikiPageWikiLink Protein_kinase_C.
- PHLPP wikiPageWikiLink Pyruvate_dehydrogenase_lipoamide_kinase_isozyme_1.
- PHLPP wikiPageWikiLink Ras_subfamily.
- PHLPP wikiPageWikiLink Retrovirus.
- PHLPP wikiPageWikiLink Serine.
- PHLPP wikiPageWikiLinkText "PHLPP".
- PHLPP wikiPageWikiLinkText "PHLPP1".
- PHLPP altsymbols "PHLPP1, PLEKHE1".
- PHLPP altsymbols "PHLPP2".
- PHLPP arm "q".
- PHLPP band "21.32".
- PHLPP band "22.2".
- PHLPP chromosome "16".
- PHLPP chromosome "18".
- PHLPP ecnumber "3.1".
- PHLPP entrezgene "23035".
- PHLPP entrezgene "23239".
- PHLPP hgncid "20610".
- PHLPP hgncid "29149".
- PHLPP name PHLPPL.
- PHLPP name PHLPP_(gene).
- PHLPP omim "609396".
- PHLPP omim "611066".
- PHLPP refseq "NM_015020".
- PHLPP refseq "XM_166290".
- PHLPP symbol PHLPPL.
- PHLPP symbol PHLPP_(gene).
- PHLPP uniprot "O60346".
- PHLPP uniprot "Q6ZVD8".
- PHLPP wikiPageUsesTemplate Template:EC_number.
- PHLPP wikiPageUsesTemplate Template:Enzymes.
- PHLPP wikiPageUsesTemplate Template:Esterases.
- PHLPP wikiPageUsesTemplate Template:Portal_bar.
- PHLPP wikiPageUsesTemplate Template:Protein.
- PHLPP wikiPageUsesTemplate Template:Reflist.
- PHLPP subject Category:EC_3.1.3.
- PHLPP subject Category:Signal_transduction.
- PHLPP hypernym Pair.
- PHLPP type Biomolecule.
- PHLPP type Place.
- PHLPP type Protein.
- PHLPP type Thing.
- PHLPP type Q206229.