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- KLRA1 abstract "Ly-49 receptors or killer cell lectin-like receptor subfamily A (KLRA), are a class of natural killer cell receptor. Ly-49 proteins are a diverse set of C-type lectins that are expressed on NK cells in some mammals, including rodents but not humans. Their primary function is to bind host MHC class I as a mechanism of self/health recognition. Upon binding ligands, most Ly-49 receptors will deliver an inhibitory signal, preventing killing of the target cell. In the case of cancer or virally infected cells, MHC-I will often be downregulated in order to limit cytotoxic T cell mediated killing of the cell, whereby NK cells will lack Ly-49 inhibitory signal and be able to kill infected or cancerous target cells.The homologous human KLRAP1 gene has been classified as a transcribed pseudogene because all associated transcripts are candidates for nonsense-mediated decay (NMD).".
- KLRA1 arm "p".
- KLRA1 band "12".
- KLRA1 chromosome "12".
- KLRA1 entrezgene "10748".
- KLRA1 hgncid "6372".
- KLRA1 locusSupplementaryData "-p13".
- KLRA1 omim "604274".
- KLRA1 refseq "NM_006611".
- KLRA1 symbol "KLRA1; Ly49; LY49L; Ly-49L".
- KLRA1 symbol "KLRAP1".
- KLRA1 uniprot "O75889".
- KLRA1 wikiPageID "10804376".
- KLRA1 wikiPageLength "3118".
- KLRA1 wikiPageOutDegree "5".
- KLRA1 wikiPageRevisionID "609966393".
- KLRA1 wikiPageWikiLink Cytotoxic_T_cell.
- KLRA1 wikiPageWikiLink Lectin.
- KLRA1 wikiPageWikiLink MHC_class_I.
- KLRA1 wikiPageWikiLink Natural_killer_cell.
- KLRA1 wikiPageWikiLink Nonsense-mediated_decay.
- KLRA1 wikiPageWikiLinkText "KLRA1".
- KLRA1 altsymbols "KLRA1; Ly49; LY49L; Ly-49L".
- KLRA1 altsymbols "Ly49b; Klra30".
- KLRA1 arm "p".
- KLRA1 band "12".
- KLRA1 chromosome "12".
- KLRA1 chromosome "6".
- KLRA1 entrezchromosome "NC_000072.6".
- KLRA1 entrezgene "10748".
- KLRA1 entrezgene "16633".
- KLRA1 genlocEnd "131251580".
- KLRA1 genlocStart "131215015".
- KLRA1 hgncid "6372".
- KLRA1 locussupplementarydata "-p13".
- KLRA1 name "Killer cell lectin-like receptor subfamily A pseudogene 1".
- KLRA1 name "killer cell lectin-like receptor, subfamily A, member 2".
- KLRA1 omim "604274".
- KLRA1 organism "Mus musculus".
- KLRA1 refseq "NM_006611".
- KLRA1 refseqmrna "NM_008462.5".
- KLRA1 refseqprotein "NP_032488.4".
- KLRA1 symbol "KLRAP1".
- KLRA1 symbol "Klra2".
- KLRA1 taxid "10090".
- KLRA1 uniprot "O75889".
- KLRA1 uniprot "Q60660".
- KLRA1 wikiPageUsesTemplate Template:Immunology-stub.
- KLRA1 wikiPageUsesTemplate Template:Infobox_nonhuman_protein.
- KLRA1 wikiPageUsesTemplate Template:MeshName.
- KLRA1 wikiPageUsesTemplate Template:Protein.
- KLRA1 wikiPageUsesTemplate Template:Reflist.
- KLRA1 hypernym Receptor.
- KLRA1 type Biomolecule.
- KLRA1 type Protein.
- KLRA1 type Chemical.
- KLRA1 type Thing.
- KLRA1 type Q206229.
- KLRA1 type Q8054.
- KLRA1 comment "Ly-49 receptors or killer cell lectin-like receptor subfamily A (KLRA), are a class of natural killer cell receptor. Ly-49 proteins are a diverse set of C-type lectins that are expressed on NK cells in some mammals, including rodents but not humans. Their primary function is to bind host MHC class I as a mechanism of self/health recognition. Upon binding ligands, most Ly-49 receptors will deliver an inhibitory signal, preventing killing of the target cell.".
- KLRA1 label "KLRA1".
- KLRA1 sameAs Q15996737.
- KLRA1 sameAs m.02qqjtr.
- KLRA1 sameAs Q15996737.
- KLRA1 wasDerivedFrom KLRA1?oldid=609966393.
- KLRA1 isPrimaryTopicOf KLRA1.
- KLRA1 name "Killer cell lectin-like receptor subfamily A pseudogene 1".