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- FKBP6 abstract "FK506 binding protein 6, also known as FKBP6, is a human gene. The encoded protein shows structural homology to FKBP immunophilins, which bind to the immunosuppressants FK506 and rapamycin.FKBP6 is essential for homologous chromosome pairing in meiosis during spermatogenesis. Targeted inactivation of FKBP6 in mice results in infertile males, but apparently normal females. Rats with spermatogenic failure at meiosis were found to have a deletion in the exon 8 portion of the FKBP6 gene. Mutations in this gene have been associated with male infertility in humans.FKBP6 is deleted in Williams syndrome, however this hemizygous loss of FKBP6 is not associated with infertility.FKBP6 contains 3 α-helices and 11 β-sheet strands, and as a FK506-family protein, has been shown to be a potent immunosuppressant which can assist in the prevention of allograft rejections.".
- FKBP6 arm "q".
- FKBP6 band "11.23".
- FKBP6 chromosome "7".
- FKBP6 entrezgene "8468".
- FKBP6 hgncid "3722".
- FKBP6 omim "604839".
- FKBP6 pdb "3B7X".
- FKBP6 refseq "NM_003602".
- FKBP6 symbol "FKBP36; MGC87179".
- FKBP6 symbol "FKBP6".
- FKBP6 thumbnail 3B7X.pdb.jpg?width=300.
- FKBP6 uniprot "O75344".
- FKBP6 wikiPageID "18220109".
- FKBP6 wikiPageLength "3456".
- FKBP6 wikiPageOutDegree "9".
- FKBP6 wikiPageRevisionID "704000896".
- FKBP6 wikiPageWikiLink Category:EC_5.2.1.
- FKBP6 wikiPageWikiLink FKBP.
- FKBP6 wikiPageWikiLink Gene.
- FKBP6 wikiPageWikiLink Immunophilins.
- FKBP6 wikiPageWikiLink Meiosis.
- FKBP6 wikiPageWikiLink Protein.
- FKBP6 wikiPageWikiLink Sirolimus.
- FKBP6 wikiPageWikiLink Tacrolimus.
- FKBP6 wikiPageWikiLink Williams_syndrome.
- FKBP6 wikiPageWikiLinkText "FKBP6".
- FKBP6 altsymbols "FKBP36; MGC87179".
- FKBP6 arm "q".
- FKBP6 band "11.23".
- FKBP6 caption "Crystal structure of human FK506-Binding Protein 6.".
- FKBP6 chromosome "7".
- FKBP6 entrezgene "8468".
- FKBP6 hgncid "3722".
- FKBP6 name "FKBP6".
- FKBP6 omim "604839".
- FKBP6 pdb "3".
- FKBP6 refseq "NM_003602".
- FKBP6 symbol "FKBP6".
- FKBP6 uniprot "O75344".
- FKBP6 wikiPageUsesTemplate Template:Enzymes.
- FKBP6 wikiPageUsesTemplate Template:Geometric_isomerases.
- FKBP6 wikiPageUsesTemplate Template:Portal_bar.
- FKBP6 wikiPageUsesTemplate Template:Protein.
- FKBP6 wikiPageUsesTemplate Template:Protein-stub.
- FKBP6 wikiPageUsesTemplate Template:Reflist.
- FKBP6 subject Category:EC_5.2.1.
- FKBP6 hypernym Gene.
- FKBP6 type Biomolecule.
- FKBP6 type Protein.
- FKBP6 type Chemical.
- FKBP6 type Thing.
- FKBP6 type Q206229.
- FKBP6 type Q8054.
- FKBP6 comment "FK506 binding protein 6, also known as FKBP6, is a human gene. The encoded protein shows structural homology to FKBP immunophilins, which bind to the immunosuppressants FK506 and rapamycin.FKBP6 is essential for homologous chromosome pairing in meiosis during spermatogenesis. Targeted inactivation of FKBP6 in mice results in infertile males, but apparently normal females. Rats with spermatogenic failure at meiosis were found to have a deletion in the exon 8 portion of the FKBP6 gene.".
- FKBP6 label "FKBP6".
- FKBP6 sameAs Q5426016.
- FKBP6 sameAs FKBP6.
- FKBP6 sameAs m.04cywj5.
- FKBP6 sameAs Q5426016.
- FKBP6 wasDerivedFrom FKBP6?oldid=704000896.
- FKBP6 depiction 3B7X.pdb.jpg.
- FKBP6 isPrimaryTopicOf FKBP6.
- FKBP6 name "FKBP6".