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- ECH1 abstract "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial is an enzyme that in humans is encoded by the ECH1 gene.This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-CoA hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, Δ3,5-Δ2,4-dienoyl-CoA isomerase, contains a C-terminal peroxisomal targeting sequence and localizes to peroxisomes. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.".
- ECH1 entrezgene "1891".
- ECH1 wikiPageID "16846909".
- ECH1 wikiPageLength "4358".
- ECH1 wikiPageOutDegree "8".
- ECH1 wikiPageRevisionID "686808397".
- ECH1 wikiPageWikiLink C-terminus.
- ECH1 wikiPageWikiLink Enoyl-CoA_hydratase.
- ECH1 wikiPageWikiLink Enzyme.
- ECH1 wikiPageWikiLink Gene.
- ECH1 wikiPageWikiLink Homology_(biology).
- ECH1 wikiPageWikiLink Isomerase.
- ECH1 wikiPageWikiLink Mitochondrion.
- ECH1 wikiPageWikiLink Peroxisome.
- ECH1 wikiPageWikiLinkText "ECH1".
- ECH1 requireManualInspection "no".
- ECH1 updateCitations "yes".
- ECH1 updatePage "yes".
- ECH1 updateProteinBox "yes".
- ECH1 updateSummary "no".
- ECH1 wikiPageUsesTemplate Template:Cite_journal.
- ECH1 wikiPageUsesTemplate Template:Gene-19-stub.
- ECH1 wikiPageUsesTemplate Template:PBB.
- ECH1 wikiPageUsesTemplate Template:PBB_Controls.
- ECH1 wikiPageUsesTemplate Template:PBB_Further_reading.
- ECH1 wikiPageUsesTemplate Template:Refbegin.
- ECH1 wikiPageUsesTemplate Template:Refend.
- ECH1 wikiPageUsesTemplate Template:Reflist.
- ECH1 hypernym Enzyme.
- ECH1 type Biomolecule.
- ECH1 type Protein.
- ECH1 type Thing.
- ECH1 type Q206229.
- ECH1 type Q8054.
- ECH1 comment "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial is an enzyme that in humans is encoded by the ECH1 gene.This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-CoA hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, Δ3,5-Δ2,4-dienoyl-CoA isomerase, contains a C-terminal peroxisomal targeting sequence and localizes to peroxisomes.".
- ECH1 label "ECH1".
- ECH1 sameAs Q17915291.
- ECH1 sameAs Delta(3,5)-delta(2,4)-diénoyl-coenzyme_A_isomérase.
- ECH1 sameAs m.040857_.
- ECH1 sameAs Q17915291.
- ECH1 wasDerivedFrom ECH1?oldid=686808397.
- ECH1 isPrimaryTopicOf ECH1.