DBpedia – Linked Data Fragments

Matches in DBpedia 2016-04 for { ?s ?p "The α-mannan Degradation. Mannan which can be found in the cell wall of yeast has aparticular chemical structure, and constitutes a food source since humans begun eating fermented foods several thousands of years ago. To determine whether the intake of yeast mannansthrough fermented foods has promoted specific adaptations of the human gutmicrobiota, an international team of researchers studied the ability of Bacteroidetes thetaiotaomicron to specifically degrade yeast mannans.The mannan-oligosaccharides are able to alter the composition of the microbiotapresent in the bowels, so they produce an increase in the growth of benignbacteria and therefore an increase in the resistance to infection by pathogens.The B. thetaiotaomicron are bacteria that have been shownto bind polysaccharides thanks to a receptor system located on the outermembrane before introducing the polysaccharides into the periplasm for theirdegradation to monosaccharides. These bacteria use α-mannose as a carbonsource. Transcriptional studies have identified three different PULs(Polysaccharide Utilization Loci) which are activated by α-Mannan from Saccharomyces cerevisiae, andSchizosaccharomyces pombe and the yeast pathogen Candida albicans.To demonstrate the specificity of these PULs, the researchers have engineereddifferent B. thetaiotaomicron strains which showed that mutants lackingMAN-PUL1, MAN-PUL3 or PUL2 are unable to grow in vitro with yeast Mannan as the solecarbon source.In order to assess whether theability to degrade yeast mannan is a general feature of the microbiota or it isa specific adaptation of B. thetaiotaomicron, the authors analysed thegrowth profiles of 29 species of Bacteroidetes on the human bowel. The analysis revealed thatonly nine are able to metabolize Saccharomyces cereviseae alfa-mannanwhile 33 of 34 strains of B. thetaiotaomicron are able to grow on this glycan. Theseresults show that B. thetaiotaomicron along with some phylogeneticallyrelated species dominate the yeast metabolism of α-Mannan in the phylumBacteroidetes of the microbial flora."@en }

• Alfa_mannan_degradation abstract "The α-mannan Degradation. Mannan which can be found in the cell wall of yeast has aparticular chemical structure, and constitutes a food source since humans begun eating fermented foods several thousands of years ago. To determine whether the intake of yeast mannansthrough fermented foods has promoted specific adaptations of the human gutmicrobiota, an international team of researchers studied the ability of Bacteroidetes thetaiotaomicron to specifically degrade yeast mannans.The mannan-oligosaccharides are able to alter the composition of the microbiotapresent in the bowels, so they produce an increase in the growth of benignbacteria and therefore an increase in the resistance to infection by pathogens.The B. thetaiotaomicron are bacteria that have been shownto bind polysaccharides thanks to a receptor system located on the outermembrane before introducing the polysaccharides into the periplasm for theirdegradation to monosaccharides. These bacteria use α-mannose as a carbonsource. Transcriptional studies have identified three different PULs(Polysaccharide Utilization Loci) which are activated by α-Mannan from Saccharomyces cerevisiae, andSchizosaccharomyces pombe and the yeast pathogen Candida albicans.To demonstrate the specificity of these PULs, the researchers have engineereddifferent B. thetaiotaomicron strains which showed that mutants lackingMAN-PUL1, MAN-PUL3 or PUL2 are unable to grow in vitro with yeast Mannan as the solecarbon source.In order to assess whether theability to degrade yeast mannan is a general feature of the microbiota or it isa specific adaptation of B. thetaiotaomicron, the authors analysed thegrowth profiles of 29 species of Bacteroidetes on the human bowel. The analysis revealed thatonly nine are able to metabolize Saccharomyces cereviseae alfa-mannanwhile 33 of 34 strains of B. thetaiotaomicron are able to grow on this glycan. Theseresults show that B. thetaiotaomicron along with some phylogeneticallyrelated species dominate the yeast metabolism of α-Mannan in the phylumBacteroidetes of the microbial flora.".