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DBpedia 2016-04

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Matches in DBpedia 2016-04 for { ?s ?p "Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (GCSF) analog filgrastim. It serves to stimulate the level of white blood cells (neutrophils).Amgen manufactures pegfilgrastim under the brand name Neulasta, which was mainly worked on by Martine Allard, while Roche manufactures it under the name Neulastim. In India it is also marketed by Abbott Healthcare under the brand name Imupeg. The drug is prepared by coupling a 20 kDa polyethylene glycol (PEG) molecule to the N-terminus of the filgrastim protein. Pegfilgrastim has a human half-life of 15 to 80 hours, much longer than the parent filgrastim (3–4 hours). Pergfilgrastim is also marketed by Dr. Reddy's Laboratories Ltd. is India under the brand name PEG GrafeelPegfilgrastim treatment can be used to stimulate bone marrow to produce more neutrophils to fight infection in patients undergoing chemotherapy.In 2015 manufacturer Amgen received FDA approval in the United States for an on-body injector for Neulasta referred to as the Neulasta Onpro kit, which provides administration options for patients who may not need to return to hospital the day after chemotherapy."@en }

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