Matches in DBpedia 2016-04 for { ?s ?p "Mitraphylline, an oxindole derivative, is an active alkaloid in the leaves of the tree Mitragyna speciosa, commonly known as kratom. As a non-narcotic constituent, it also occurs to a significant amount in the bark of Uncaria tomentosa (Cat’s Claw) along with a number of isomeric alkaloids. Due to its structural similarity to mitragynine and 7-hydroxymitragynine from kratom, effects on mu and delta opiate receptors as well as NMDA-antagonistic actions have been postulated.Current research is focussing on antiproliferative and cytotoxic effects and its in vivo efficacy to induce apoptosis in human breast cancer, sarcoma as well as lymphoblastic leukaemia cell lines."@en }
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- Mitraphylline abstract "Mitraphylline, an oxindole derivative, is an active alkaloid in the leaves of the tree Mitragyna speciosa, commonly known as kratom. As a non-narcotic constituent, it also occurs to a significant amount in the bark of Uncaria tomentosa (Cat’s Claw) along with a number of isomeric alkaloids. Due to its structural similarity to mitragynine and 7-hydroxymitragynine from kratom, effects on mu and delta opiate receptors as well as NMDA-antagonistic actions have been postulated.Current research is focussing on antiproliferative and cytotoxic effects and its in vivo efficacy to induce apoptosis in human breast cancer, sarcoma as well as lymphoblastic leukaemia cell lines.".
- Q10859059 abstract "Mitraphylline, an oxindole derivative, is an active alkaloid in the leaves of the tree Mitragyna speciosa, commonly known as kratom. As a non-narcotic constituent, it also occurs to a significant amount in the bark of Uncaria tomentosa (Cat’s Claw) along with a number of isomeric alkaloids. Due to its structural similarity to mitragynine and 7-hydroxymitragynine from kratom, effects on mu and delta opiate receptors as well as NMDA-antagonistic actions have been postulated.Current research is focussing on antiproliferative and cytotoxic effects and its in vivo efficacy to induce apoptosis in human breast cancer, sarcoma as well as lymphoblastic leukaemia cell lines.".