Matches in DBpedia 2016-04 for { ?s ?p "Maternal effect dominant embryonic arrest (Medea) is a selfish gene composed of a toxin and an antidote. A mother carrying Medea will express the toxin in her germline, killing her progeny. If the children also carry Medea, they produce copies of the antidote, saving their lives. Therefore, if a mother has one Medea allele and one non-Medea allele, half of her children will inherit Medea and survive while the other half will inherit the non-Medea allele and die (unless they receive Medea from their father).Medea's selfish behavior gives it a selective advantage over normal genes. If introduced into a population at sufficiently high levels, the Medea gene will spread, replacing entire populations of normal beetles with beetles carrying Medea. Because of this, Medea has been proposed as a way of genetically modifying insect populations. By linking the Medea construct to a gene of interest - for instance, a gene conferring resistance to malaria - Medea's unique dynamics could be exploited to drive both genes into a population. These findings have dramatic implications for the control of insect-borne diseases such as malaria and dengue fever."@en }
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- Maternal_effect_dominant_embryonic_arrest abstract "Maternal effect dominant embryonic arrest (Medea) is a selfish gene composed of a toxin and an antidote. A mother carrying Medea will express the toxin in her germline, killing her progeny. If the children also carry Medea, they produce copies of the antidote, saving their lives. Therefore, if a mother has one Medea allele and one non-Medea allele, half of her children will inherit Medea and survive while the other half will inherit the non-Medea allele and die (unless they receive Medea from their father).Medea's selfish behavior gives it a selective advantage over normal genes. If introduced into a population at sufficiently high levels, the Medea gene will spread, replacing entire populations of normal beetles with beetles carrying Medea. Because of this, Medea has been proposed as a way of genetically modifying insect populations. By linking the Medea construct to a gene of interest - for instance, a gene conferring resistance to malaria - Medea's unique dynamics could be exploited to drive both genes into a population. These findings have dramatic implications for the control of insect-borne diseases such as malaria and dengue fever.".
- Q599579 abstract "Maternal effect dominant embryonic arrest (Medea) is a selfish gene composed of a toxin and an antidote. A mother carrying Medea will express the toxin in her germline, killing her progeny. If the children also carry Medea, they produce copies of the antidote, saving their lives. Therefore, if a mother has one Medea allele and one non-Medea allele, half of her children will inherit Medea and survive while the other half will inherit the non-Medea allele and die (unless they receive Medea from their father).Medea's selfish behavior gives it a selective advantage over normal genes. If introduced into a population at sufficiently high levels, the Medea gene will spread, replacing entire populations of normal beetles with beetles carrying Medea. Because of this, Medea has been proposed as a way of genetically modifying insect populations. By linking the Medea construct to a gene of interest - for instance, a gene conferring resistance to malaria - Medea's unique dynamics could be exploited to drive both genes into a population. These findings have dramatic implications for the control of insect-borne diseases such as malaria and dengue fever.".