Matches in DBpedia 2016-04 for { ?s ?p "In toxicology, the median lethal dose, LD50 (abbreviation for \"lethal dose, 50%\"), LC50 (lethal concentration, 50%) or LCt50 is a measure of the lethal dose of a toxin, radiation, or pathogen. The value of LD50 for a substance is the dose required to kill half the members of a tested population after a specified test duration. LD50 figures are frequently used as a general indicator of a substance's acute toxicity. A lower LD50 is indicative of increased toxicity.The test was created by J.W. Trevan in 1927. The term semilethal dose is occasionally used with the same meaning, in particular in translations from non-English-language texts, but can also refer to a sublethal dose; because of this ambiguity, it is usually avoided. LD50 is usually determined by tests on animals such as laboratory mice.In 2011 the US Food and Drug Administration approved alternative methods to LD50 for testing the cosmetic drug BOTOX without animal tests."@en }
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- Median_lethal_dose abstract "In toxicology, the median lethal dose, LD50 (abbreviation for \"lethal dose, 50%\"), LC50 (lethal concentration, 50%) or LCt50 is a measure of the lethal dose of a toxin, radiation, or pathogen. The value of LD50 for a substance is the dose required to kill half the members of a tested population after a specified test duration. LD50 figures are frequently used as a general indicator of a substance's acute toxicity. A lower LD50 is indicative of increased toxicity.The test was created by J.W. Trevan in 1927. The term semilethal dose is occasionally used with the same meaning, in particular in translations from non-English-language texts, but can also refer to a sublethal dose; because of this ambiguity, it is usually avoided. LD50 is usually determined by tests on animals such as laboratory mice.In 2011 the US Food and Drug Administration approved alternative methods to LD50 for testing the cosmetic drug BOTOX without animal tests.".