Matches in DBpedia 2016-04 for { ?s ?p "In chemistry a convergent synthesis is a strategy that aims to improve the efficiency of multistep synthesis, most often in organic synthesis. In this type of synthesis several individual pieces of a complex molecule are synthesized in stage one and then in stage two these pieces are combined to form the final product In linear synthesis the overall yield quickly drops with each reaction step:A → B → C → DSuppose the yield is 50% for each reaction, the overall yield of D is only 12.5% from A.In a convergent synthesisA → B (50%)C → D (50%)B + D → E (25%)the overall yield of E (25%) looks much better. Convergent synthesis is applied in the synthesis of complex molecules and involve fragment coupling and independent synthesis.Examples: Convergent synthesis is encountered in dendrimer synthesis where branches (with the number of generations preset) are connected to the central core Proteins of up to 300 amino acids are produced by a convergent approach using chemical ligation. An example of its use in total synthesis is the final step (photochemical [2+2]cycloaddition) towards the compound Biyouyanagin A:Final step in total synthesis of Biyouyanagin A with acetonaphthone photosensitizer↑ ↑ ↑"@en }
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- Convergent_synthesis abstract "In chemistry a convergent synthesis is a strategy that aims to improve the efficiency of multistep synthesis, most often in organic synthesis. In this type of synthesis several individual pieces of a complex molecule are synthesized in stage one and then in stage two these pieces are combined to form the final product In linear synthesis the overall yield quickly drops with each reaction step:A → B → C → DSuppose the yield is 50% for each reaction, the overall yield of D is only 12.5% from A.In a convergent synthesisA → B (50%)C → D (50%)B + D → E (25%)the overall yield of E (25%) looks much better. Convergent synthesis is applied in the synthesis of complex molecules and involve fragment coupling and independent synthesis.Examples: Convergent synthesis is encountered in dendrimer synthesis where branches (with the number of generations preset) are connected to the central core Proteins of up to 300 amino acids are produced by a convergent approach using chemical ligation. An example of its use in total synthesis is the final step (photochemical [2+2]cycloaddition) towards the compound Biyouyanagin A:Final step in total synthesis of Biyouyanagin A with acetonaphthone photosensitizer↑ ↑ ↑".
- Q2687640 abstract "In chemistry a convergent synthesis is a strategy that aims to improve the efficiency of multistep synthesis, most often in organic synthesis. In this type of synthesis several individual pieces of a complex molecule are synthesized in stage one and then in stage two these pieces are combined to form the final product In linear synthesis the overall yield quickly drops with each reaction step:A → B → C → DSuppose the yield is 50% for each reaction, the overall yield of D is only 12.5% from A.In a convergent synthesisA → B (50%)C → D (50%)B + D → E (25%)the overall yield of E (25%) looks much better. Convergent synthesis is applied in the synthesis of complex molecules and involve fragment coupling and independent synthesis.Examples: Convergent synthesis is encountered in dendrimer synthesis where branches (with the number of generations preset) are connected to the central core Proteins of up to 300 amino acids are produced by a convergent approach using chemical ligation. An example of its use in total synthesis is the final step (photochemical [2+2]cycloaddition) towards the compound Biyouyanagin A:Final step in total synthesis of Biyouyanagin A with acetonaphthone photosensitizer↑ ↑ ↑".