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DBpedia 2016-04

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Matches in DBpedia 2016-04 for { ?s ?p "Goserelin acetate (trade name Zoladex, by AstraZeneca) is a drug used to suppress production of the sex hormones (testosterone and estrogen), particularly in the treatment of breast and prostate cancer. It is an injectable gonadotropin releasing hormone superagonist (GnRH agonist), also known as a luteinizing hormone releasing hormone (LHRH) agonist. Structurally, it is a decapeptide.Goserelin acetate stimulates the production of the sex hormones testosterone and estrogen in a non-pulsatile (non-physiological) manner. This causes the disruption of the endogenous hormonal feedback systems, resulting in the down-regulation of testosterone and estrogen production.Zoladex was approved by the U.S. Food and Drug Administration in 1989 for treatment of prostate cancer."@en }

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