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DBpedia 2016-04

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Matches in DBpedia 2016-04 for { ?s ?p "General transcription factors (GTFs), also known as basal transcriptional factors, are a class of protein transcription factors that bind to specific sites (promoter) on DNA to activate transcription of genetic information from DNA to messenger RNA. GTFs, RNA polymerase, and the mediator multiple protein complex constitute the basic transcriptional apparatus that bind to the promoter, then start transcription. GTFs are also intimately involved in the process of gene regulation, and most are required for life.A transcription factor is a protein that binds to specific DNA sequences (enhancer or promoter), alone or with other proteins in a complex, to control the rate of transcription of genetic information from DNA to messenger RNA by promoting as an activator or blocking as a repressor the recruitment of RNA polymerase. As a class of protein, general transcription factors bind to promoters along the DNA sequence or form a large transcription preinitiation complex to activate transcription. General transcription factors are necessary for transcription to occur."@en }

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