Matches in DBpedia 2016-04 for { ?s ?p "Evolocumab (INN, trade name Repatha) is a monoclonal antibody designed for the treatment of hyperlipidemia by Amgen. Evolocumab is a fully human monoclonal antibody that inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9).PCSK9 is a protein that targets LDL receptors for degradation and thereby reduces the liver's ability to remove LDL-C, or \"bad\" cholesterol, from the blood.Evolocumab is designed to bind to PCSK9 and inhibit PCSK9 from binding to LDL receptors on the liver surface. In the absence of PCSK9, there are more LDL receptors on the surface of the liver to remove LDL-C from the blood."@en }
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- Evolocumab abstract "Evolocumab (INN, trade name Repatha) is a monoclonal antibody designed for the treatment of hyperlipidemia by Amgen. Evolocumab is a fully human monoclonal antibody that inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9).PCSK9 is a protein that targets LDL receptors for degradation and thereby reduces the liver's ability to remove LDL-C, or \"bad\" cholesterol, from the blood.Evolocumab is designed to bind to PCSK9 and inhibit PCSK9 from binding to LDL receptors on the liver surface. In the absence of PCSK9, there are more LDL receptors on the surface of the liver to remove LDL-C from the blood.".