DBpedia – Linked Data Fragments

DBpedia 2016-04

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Matches in DBpedia 2016-04 for { ?s ?p "Dopamine beta-hydroxylase (DBH), also known as dopamine beta-monooxygenase, is an enzyme (EC 1.14.17.1) that in humans is encoded by the DBH gene. Dopamine beta-hydroxylase catalyzes the chemical reaction:The three substrates of this enzyme are 3,4-dihydroxyphenethylamine, ascorbate, and O2, whereas its three products are noradrenaline, dehydroascorbate, and H2O.DBH is a 290 kDa copper-containing oxygenase consisting of four identical subunits, and its activity requires ascorbate as a cofactor.It is the only enzyme involved in the synthesis of small-molecule neurotransmitters that is membrane-bound, making norepinephrine the only transmitter synthesized inside vesicles. It is expressed in noradrenergic nerve terminals of the central and peripheral nervous systems, as well as in chromaffin cells of the adrenal medulla."@en }

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