Matches in DBpedia 2016-04 for { ?s ?p "Cytochrome P450 2C9 (CYP2C9), a member of the CYP2C enzyme subfamily, ranks amongst the mostimportant drug metabolizing enzymes in humans.Human CYP2C9 has been shown to exhibit genetic polymorphism. In addition to the wild-type protein CYP2C9*1, at least 32 single nucleotide polymorphisms (SNPs) have been reported within the coding region of the CYP2C9 gene producing the variant allozymes. CYP2C9*3 is one of them. CYP2C9*3 reflects an Ile359-Leu (I359L) change in the amino acid sequence, and have reduced catalytic activity compared with the wild type (CYP2C9*1)."@en }
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- CYP2C9*3 abstract "Cytochrome P450 2C9 (CYP2C9), a member of the CYP2C enzyme subfamily, ranks amongst the mostimportant drug metabolizing enzymes in humans.Human CYP2C9 has been shown to exhibit genetic polymorphism. In addition to the wild-type protein CYP2C9*1, at least 32 single nucleotide polymorphisms (SNPs) have been reported within the coding region of the CYP2C9 gene producing the variant allozymes. CYP2C9*3 is one of them. CYP2C9*3 reflects an Ile359-Leu (I359L) change in the amino acid sequence, and have reduced catalytic activity compared with the wild type (CYP2C9*1).".
- Q5014960 abstract "Cytochrome P450 2C9 (CYP2C9), a member of the CYP2C enzyme subfamily, ranks amongst the mostimportant drug metabolizing enzymes in humans.Human CYP2C9 has been shown to exhibit genetic polymorphism. In addition to the wild-type protein CYP2C9*1, at least 32 single nucleotide polymorphisms (SNPs) have been reported within the coding region of the CYP2C9 gene producing the variant allozymes. CYP2C9*3 is one of them. CYP2C9*3 reflects an Ile359-Leu (I359L) change in the amino acid sequence, and have reduced catalytic activity compared with the wild type (CYP2C9*1).".