Matches in DBpedia 2016-04 for { ?s ?p "Auger therapy (AT) is a form of radiation therapy for the treatment of cancer which relies on a large number of low-energy electrons (emitted by the Auger effect) to damage cancer cells, rather than the high-energy radiation used in traditional radiation therapy. Similar to other forms of radiation therapy, Auger therapy relies on radiation-induced damage to cancer cells (particularly DNA damage) to arrest cell division, stop tumor growth and metastasis and kill cancerous cells. It differs from other types of radiation therapy in that electrons emitted via the Auger effect (Auger electrons) are released in large numbers with low kinetic energy. Because of their low energy, these electrons damage cells over a very short range: less than the size of a single cell, on the order of nanometers. This very short-range delivery of energy permits highly targeted therapies, since the radiation-emitting nuclide is required to be inside the cell to cause damage to its nucleus. However, this is a technical challenge; Auger therapeutics must enter their cellular targets to be most effective. Auger therapeutics are small molecules, capable of entering cells of interest and binding to specific sub-cellular components, which contain one (or more) heavy atoms capable of emitting Auger electrons by radioactive decay or external excitation."@en }
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- Auger_therapy abstract "Auger therapy (AT) is a form of radiation therapy for the treatment of cancer which relies on a large number of low-energy electrons (emitted by the Auger effect) to damage cancer cells, rather than the high-energy radiation used in traditional radiation therapy. Similar to other forms of radiation therapy, Auger therapy relies on radiation-induced damage to cancer cells (particularly DNA damage) to arrest cell division, stop tumor growth and metastasis and kill cancerous cells. It differs from other types of radiation therapy in that electrons emitted via the Auger effect (Auger electrons) are released in large numbers with low kinetic energy. Because of their low energy, these electrons damage cells over a very short range: less than the size of a single cell, on the order of nanometers. This very short-range delivery of energy permits highly targeted therapies, since the radiation-emitting nuclide is required to be inside the cell to cause damage to its nucleus. However, this is a technical challenge; Auger therapeutics must enter their cellular targets to be most effective. Auger therapeutics are small molecules, capable of entering cells of interest and binding to specific sub-cellular components, which contain one (or more) heavy atoms capable of emitting Auger electrons by radioactive decay or external excitation.".
- Q4820344 abstract "Auger therapy (AT) is a form of radiation therapy for the treatment of cancer which relies on a large number of low-energy electrons (emitted by the Auger effect) to damage cancer cells, rather than the high-energy radiation used in traditional radiation therapy. Similar to other forms of radiation therapy, Auger therapy relies on radiation-induced damage to cancer cells (particularly DNA damage) to arrest cell division, stop tumor growth and metastasis and kill cancerous cells. It differs from other types of radiation therapy in that electrons emitted via the Auger effect (Auger electrons) are released in large numbers with low kinetic energy. Because of their low energy, these electrons damage cells over a very short range: less than the size of a single cell, on the order of nanometers. This very short-range delivery of energy permits highly targeted therapies, since the radiation-emitting nuclide is required to be inside the cell to cause damage to its nucleus. However, this is a technical challenge; Auger therapeutics must enter their cellular targets to be most effective. Auger therapeutics are small molecules, capable of entering cells of interest and binding to specific sub-cellular components, which contain one (or more) heavy atoms capable of emitting Auger electrons by radioactive decay or external excitation.".