DBpedia – Linked Data Fragments

DBpedia 2016-04

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Matches in DBpedia 2016-04 for { ?s ?p "26S proteasome non-ATPase regulatory subunit 7 , also known as 26S proteasome non-ATPase subunit Rpn8,is an enzyme that in humans is encoded by the PSMD7 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides."@en }

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