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- TGM5 abstract "TGM5 is a transglutaminase enzyme.TGM5 encodes one member of the multigene transglutaminase family. Transglutaminases (TGs) are involved in protein cross-linking by catalyzing the formation of gamma-glutamyl-lysine isodipeptide bonds between adjacent polypeptides (Candi et al. 2005; Eckert et al. 2005). This process is particularly important in the terminal differentiation of the epidermis, where TGs heavily cross-link keratins and a range of differentiation-specific structural proteins, such as involucrin, loricrin, filaggrin, and small proline-rich proteins, in the formation of the cornified cell envelope in the biogenesis of the stratum corneum, the outermost, “dead” layer of the epidermis (Kalinin et al. 2002). This continuously shed outer layer of the epidermis performs the main barrier function of the skin. Recessive loss-of-function mutations in TGM1 have been shown to cause lamellar ichthyosis, a disease characterized by excessive scaling and shedding of the outer epidermis (Huber et al. 1995; Parmentier et al. 1995; Russell et al. 1995).".
- TGM5 arm "q".
- TGM5 band "15.2".
- TGM5 chromosome "15".
- TGM5 ecNumber "2.3.2.13".
- TGM5 entrezgene "9333".
- TGM5 hgncid "11781".
- TGM5 omim "603805".
- TGM5 refseq "NM_201631".
- TGM5 symbol "TGM5".
- TGM5 symbol "Transglutaminase X, TGX".
- TGM5 uniprot "O43548".
- TGM5 wikiPageID "30254609".
- TGM5 wikiPageLength "3615".
- TGM5 wikiPageOutDegree "3".
- TGM5 wikiPageRevisionID "679092743".
- TGM5 wikiPageWikiLink Enzyme.
- TGM5 wikiPageWikiLink Peeling_skin_syndrome.
- TGM5 wikiPageWikiLink Transglutaminase.
- TGM5 wikiPageWikiLinkText "TGM5".
- TGM5 wikiPageWikiLinkText "Transglutaminase 5".
- TGM5 altsymbols "Transglutaminase X, TGX".
- TGM5 arm "q".
- TGM5 band "15.2".
- TGM5 chromosome "15".
- TGM5 ecnumber "2.3".
- TGM5 entrezgene "9333".
- TGM5 hasPhotoCollection TGM5.
- TGM5 hgncid "11781".
- TGM5 name "transglutaminase 5".
- TGM5 omim "603805".
- TGM5 refseq "NM_201631".
- TGM5 symbol "TGM5".
- TGM5 uniprot "O43548".
- TGM5 wikiPageUsesTemplate Template:Acyltransferases.
- TGM5 wikiPageUsesTemplate Template:Enzyme-stub.
- TGM5 wikiPageUsesTemplate Template:Protein.
- TGM5 wikiPageUsesTemplate Template:Reflist.
- TGM5 hypernym Member.
- TGM5 type Biomolecule.
- TGM5 type Person.
- TGM5 type Protein.
- TGM5 type Thing.
- TGM5 type Q206229.
- TGM5 type Q8054.
- TGM5 comment "TGM5 is a transglutaminase enzyme.TGM5 encodes one member of the multigene transglutaminase family. Transglutaminases (TGs) are involved in protein cross-linking by catalyzing the formation of gamma-glutamyl-lysine isodipeptide bonds between adjacent polypeptides (Candi et al. 2005; Eckert et al. 2005).".
- TGM5 label "TGM5".
- TGM5 sameAs m.0g58th9.
- TGM5 sameAs Q7670170.
- TGM5 sameAs Q7670170.
- TGM5 wasDerivedFrom TGM5?oldid=679092743.
- TGM5 isPrimaryTopicOf TGM5.