Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Orosomucoid> ?p ?o }
- Orosomucoid abstract "Orosomucoid (ORM) or alpha-1-acid glycoprotein (α1AGp, AGP or AAG) is an acute phase (acute phase protein) plasma alpha-globulin glycoprotein and is modulated by two polymorphic genes. It is synthesized primarily in hepatocytes and has a normal plasma concentration between 0.6-1.2 mg/mL (1-3% plasma protein). Plasma levels are affected by pregnancy, burns, certain drugs, and certain diseases, particularly HIV.The only established function of ORM is to act as a carrier of basic and neutrally charged lipophilic compounds. In medicine, it is known as the primary carrier of basic (positively charged) drugs (whereas albumin carries acidic (negatively charged) and neutral drugs), steroids, and protease inhibitors. Aging causes a small decrease in plasma albumin levels; if anything, there is a small increase in alpha-1-acid glycoprotein. The effect of these changes on drug protein binding and drug delivery, however, appear to be minimal. AGP shows a complex interaction with thyroid homeostasis: ORM in low concentrations was observed to stimulate the thyrotropin (TSH) receptor and intracellular accumulation of cyclic AMP. High AGP concentrations, however, inhibited TSH signalling.Alpha-1-acid glycoprotein has been identified as one of four potentially useful circulating biomarkers for estimating the five-year risk of all-cause mortality (the other three are albumin, very low-density lipoprotein particle size, and citrate).Orosomucoid increases in amount in obstructive jaundices while diminishes in hepatocellular jaundice and in intestinal infections.".
- Orosomucoid arm "q".
- Orosomucoid band "31".
- Orosomucoid chromosome "9".
- Orosomucoid entrezgene "5004".
- Orosomucoid entrezgene "5005".
- Orosomucoid hgncid "8498".
- Orosomucoid hgncid "8499".
- Orosomucoid locusSupplementaryData "-qter".
- Orosomucoid omim "138600".
- Orosomucoid omim "138610".
- Orosomucoid refseq "NM_000607".
- Orosomucoid refseq "NM_000608".
- Orosomucoid symbol "ORM1".
- Orosomucoid symbol "ORM2".
- Orosomucoid uniprot "P02763".
- Orosomucoid uniprot "P19652".
- Orosomucoid wikiPageID "7362120".
- Orosomucoid wikiPageLength "4735".
- Orosomucoid wikiPageOutDegree "27".
- Orosomucoid wikiPageRevisionID "678998725".
- Orosomucoid wikiPageWikiLink Acute-phase_protein.
- Orosomucoid wikiPageWikiLink Acute_phase_protein.
- Orosomucoid wikiPageWikiLink Albumin.
- Orosomucoid wikiPageWikiLink Alpha-globulin.
- Orosomucoid wikiPageWikiLink Alpha_globulin.
- Orosomucoid wikiPageWikiLink Blood_plasma.
- Orosomucoid wikiPageWikiLink Category:Acute_phase_proteins.
- Orosomucoid wikiPageWikiLink Category:Glycoproteins.
- Orosomucoid wikiPageWikiLink Category:Molecular_biology.
- Orosomucoid wikiPageWikiLink Category:Proteomics.
- Orosomucoid wikiPageWikiLink Citrate.
- Orosomucoid wikiPageWikiLink Cyclic_AMP.
- Orosomucoid wikiPageWikiLink Cyclic_adenosine_monophosphate.
- Orosomucoid wikiPageWikiLink Glycoprotein.
- Orosomucoid wikiPageWikiLink HIV.
- Orosomucoid wikiPageWikiLink Hepatocellular_jaundice.
- Orosomucoid wikiPageWikiLink Hepatocyte.
- Orosomucoid wikiPageWikiLink Human_gastrointestinal_tract.
- Orosomucoid wikiPageWikiLink Infection.
- Orosomucoid wikiPageWikiLink Intestinal.
- Orosomucoid wikiPageWikiLink Jaundice.
- Orosomucoid wikiPageWikiLink ORM1.
- Orosomucoid wikiPageWikiLink Obstructive_jaundice.
- Orosomucoid wikiPageWikiLink Polymorphic_gene.
- Orosomucoid wikiPageWikiLink Pregnancy.
- Orosomucoid wikiPageWikiLink Protease_inhibitor_(pharmacology).
- Orosomucoid wikiPageWikiLink Serum_albumin.
- Orosomucoid wikiPageWikiLink Steroid.
- Orosomucoid wikiPageWikiLink Thyroid.
- Orosomucoid wikiPageWikiLink Thyroid-stimulating_hormone.
- Orosomucoid wikiPageWikiLink Thyrotropin.
- Orosomucoid wikiPageWikiLink Very_low-density_lipoprotein.
- Orosomucoid wikiPageWikiLinkText "Orosomucoid".
- Orosomucoid wikiPageWikiLinkText "alpha 1-acid glycoprotein".
- Orosomucoid wikiPageWikiLinkText "alpha-1 acid glycoprotein".
- Orosomucoid wikiPageWikiLinkText "orosomucoid".
- Orosomucoid arm "q".
- Orosomucoid band "31".
- Orosomucoid chromosome "9".
- Orosomucoid entrezgene "5004".
- Orosomucoid entrezgene "5005".
- Orosomucoid hasPhotoCollection Orosomucoid.
- Orosomucoid hgncid "8498".
- Orosomucoid hgncid "8499".
- Orosomucoid locussupplementarydata "-qter".
- Orosomucoid name ORM1.
- Orosomucoid name "orosomucoid 2".
- Orosomucoid omim "138600".
- Orosomucoid omim "138610".
- Orosomucoid refseq "NM_000607".
- Orosomucoid refseq "NM_000608".
- Orosomucoid symbol ORM1.
- Orosomucoid symbol "ORM2".
- Orosomucoid uniprot "P02763".
- Orosomucoid uniprot "P19652".
- Orosomucoid wikiPageUsesTemplate Template:Acute_phase_proteins.
- Orosomucoid wikiPageUsesTemplate Template:Alpha_globulins.
- Orosomucoid wikiPageUsesTemplate Template:Gene-9-stub.
- Orosomucoid wikiPageUsesTemplate Template:MeshName.
- Orosomucoid wikiPageUsesTemplate Template:Mucoproteins.
- Orosomucoid wikiPageUsesTemplate Template:Protein.
- Orosomucoid wikiPageUsesTemplate Template:Reflist.
- Orosomucoid subject Category:Acute_phase_proteins.
- Orosomucoid subject Category:Glycoproteins.
- Orosomucoid subject Category:Molecular_biology.
- Orosomucoid subject Category:Proteomics.
- Orosomucoid hypernym Glycoprotein.
- Orosomucoid type Biomolecule.
- Orosomucoid type Protein.
- Orosomucoid type Glycoprotein.
- Orosomucoid type Omic.
- Orosomucoid type Proteomic.
- Orosomucoid type Thing.
- Orosomucoid type Q206229.
- Orosomucoid type Q8054.
- Orosomucoid comment "Orosomucoid (ORM) or alpha-1-acid glycoprotein (α1AGp, AGP or AAG) is an acute phase (acute phase protein) plasma alpha-globulin glycoprotein and is modulated by two polymorphic genes. It is synthesized primarily in hepatocytes and has a normal plasma concentration between 0.6-1.2 mg/mL (1-3% plasma protein).".
- Orosomucoid label "Orosomucoid".
- Orosomucoid sameAs Orosomukoid.
- Orosomucoid sameAs آلفا-۱-اسید_گلیکوپروتئین.