Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Ligand_(biochemistry)> ?p ?o }
- Ligand_(biochemistry) abstract "In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose. In protein-ligand binding, the ligand is usually a signal-triggering molecule binding to a site on a target protein. The binding typically results in a change of conformation of the target protein. In DNA-ligand binding studies, the ligand can be a small molecule, ion, or protein that binds to the DNA double helix.The binding occurs by intermolecular forces, such as ionic bonds, hydrogen bonds and van der Waals forces. The docking (association) is usually reversible (dissociation). Actual irreversible covalent bonding between a ligand and its target molecule is rare in biological systems. In contrast to the meaning in metalorganic and inorganic chemistry, it is irrelevant whether the ligand actually binds at a metal site, as is the case in hemoglobin.Ligand binding to a receptor (receptor protein) alters its chemical conformation (three-dimensional shape). The conformational state of a receptor protein determines its functional state. Ligands include substrates, inhibitors, activators, and neurotransmitters. The tendency or strength of binding is called affinity. Binding affinity is determined not only by direct interactions, but also by solvent effects that can play a dominant indirect role in driving non-covalent binding in solution.Radioligands are radioisotope labeled compounds are used in vivo as tracers in PET studies and for in vitro binding studies.".
- Ligand_(biochemistry) thumbnail Myoglobin_and_heme.png?width=300.
- Ligand_(biochemistry) wikiPageExternalLink www.bindingdb.org.
- Ligand_(biochemistry) wikiPageExternalLink BioLiP.
- Ligand_(biochemistry) wikiPageID "2202422".
- Ligand_(biochemistry) wikiPageLength "13370".
- Ligand_(biochemistry) wikiPageOutDegree "70".
- Ligand_(biochemistry) wikiPageRevisionID "682918333".
- Ligand_(biochemistry) wikiPageWikiLink Activator_(proteomics).
- Ligand_(biochemistry) wikiPageWikiLink Adverse_effect.
- Ligand_(biochemistry) wikiPageWikiLink Adverse_effects.
- Ligand_(biochemistry) wikiPageWikiLink Agonist.
- Ligand_(biochemistry) wikiPageWikiLink Allosteric_regulation.
- Ligand_(biochemistry) wikiPageWikiLink Binding_site.
- Ligand_(biochemistry) wikiPageWikiLink Biochemistry.
- Ligand_(biochemistry) wikiPageWikiLink Biomolecule.
- Ligand_(biochemistry) wikiPageWikiLink Carbon_monoxide.
- Ligand_(biochemistry) wikiPageWikiLink Carbon_monoxide_poisoning.
- Ligand_(biochemistry) wikiPageWikiLink Category:Biomolecules.
- Ligand_(biochemistry) wikiPageWikiLink Category:Cell_signaling.
- Ligand_(biochemistry) wikiPageWikiLink Category:Chemical_bonding.
- Ligand_(biochemistry) wikiPageWikiLink Category:Ligands.
- Ligand_(biochemistry) wikiPageWikiLink Category:Proteins.
- Ligand_(biochemistry) wikiPageWikiLink Chemical_conformation.
- Ligand_(biochemistry) wikiPageWikiLink Chemical_structure.
- Ligand_(biochemistry) wikiPageWikiLink Complex_(chemistry).
- Ligand_(biochemistry) wikiPageWikiLink Concentration.
- Ligand_(biochemistry) wikiPageWikiLink Configuration_integral.
- Ligand_(biochemistry) wikiPageWikiLink Coordination_complex.
- Ligand_(biochemistry) wikiPageWikiLink Covalent.
- Ligand_(biochemistry) wikiPageWikiLink Covalent_bond.
- Ligand_(biochemistry) wikiPageWikiLink DNA-binding_protein.
- Ligand_(biochemistry) wikiPageWikiLink DNA_binding_ligand.
- Ligand_(biochemistry) wikiPageWikiLink Dissociation_constant.
- Ligand_(biochemistry) wikiPageWikiLink Docking@Home.
- Ligand_(biochemistry) wikiPageWikiLink Docking_(molecular).
- Ligand_(biochemistry) wikiPageWikiLink Drug.
- Ligand_(biochemistry) wikiPageWikiLink Drugs.
- Ligand_(biochemistry) wikiPageWikiLink Dual-polarization_interferometry.
- Ligand_(biochemistry) wikiPageWikiLink Dual_polarisation_interferometry.
- Ligand_(biochemistry) wikiPageWikiLink Enzyme.
- Ligand_(biochemistry) wikiPageWikiLink Enzyme_activator.
- Ligand_(biochemistry) wikiPageWikiLink Enzyme_inhibitor.
- Ligand_(biochemistry) wikiPageWikiLink GPCR_oligomer.
- Ligand_(biochemistry) wikiPageWikiLink GPUGRID.net.
- Ligand_(biochemistry) wikiPageWikiLink Hemoglobin.
- Ligand_(biochemistry) wikiPageWikiLink Hydrogen_bond.
- Ligand_(biochemistry) wikiPageWikiLink IC50.
- Ligand_(biochemistry) wikiPageWikiLink In_vitro.
- Ligand_(biochemistry) wikiPageWikiLink In_vivo.
- Ligand_(biochemistry) wikiPageWikiLink Inorganic_chemistry.
- Ligand_(biochemistry) wikiPageWikiLink Intermolecular_force.
- Ligand_(biochemistry) wikiPageWikiLink Inverse_agonist.
- Ligand_(biochemistry) wikiPageWikiLink Ionic_bond.
- Ligand_(biochemistry) wikiPageWikiLink Ionic_bonding.
- Ligand_(biochemistry) wikiPageWikiLink Isotopic_labeling.
- Ligand_(biochemistry) wikiPageWikiLink Ki_Database.
- Ligand_(biochemistry) wikiPageWikiLink Ligand.
- Ligand_(biochemistry) wikiPageWikiLink Ligand-gated_ion_channel.
- Ligand_(biochemistry) wikiPageWikiLink Lipinskis_rule_of_five.
- Ligand_(biochemistry) wikiPageWikiLink Metal.
- Ligand_(biochemistry) wikiPageWikiLink Metalorganic.
- Ligand_(biochemistry) wikiPageWikiLink Metalorganics.
- Ligand_(biochemistry) wikiPageWikiLink Microscale_Thermophoresis.
- Ligand_(biochemistry) wikiPageWikiLink Microscale_thermophoresis.
- Ligand_(biochemistry) wikiPageWikiLink Nano-.
- Ligand_(biochemistry) wikiPageWikiLink Neurotransmitter.
- Ligand_(biochemistry) wikiPageWikiLink Oxygen.
- Ligand_(biochemistry) wikiPageWikiLink Partition_function_(statistical_mechanics).
- Ligand_(biochemistry) wikiPageWikiLink Pharmacology.
- Ligand_(biochemistry) wikiPageWikiLink Positron_emission_tomography.
- Ligand_(biochemistry) wikiPageWikiLink Protein.
- Ligand_(biochemistry) wikiPageWikiLink Radioactive_tracer.
- Ligand_(biochemistry) wikiPageWikiLink Radioisotope.
- Ligand_(biochemistry) wikiPageWikiLink Radiolabel.
- Ligand_(biochemistry) wikiPageWikiLink Radioligand.
- Ligand_(biochemistry) wikiPageWikiLink Radionuclide.
- Ligand_(biochemistry) wikiPageWikiLink Receptor_(biochemistry).
- Ligand_(biochemistry) wikiPageWikiLink Receptor_antagonist.
- Ligand_(biochemistry) wikiPageWikiLink Rule_of_five.
- Ligand_(biochemistry) wikiPageWikiLink Schild_regression.
- Ligand_(biochemistry) wikiPageWikiLink Statistical_mechanics.
- Ligand_(biochemistry) wikiPageWikiLink Substrate_(biochemistry).
- Ligand_(biochemistry) wikiPageWikiLink Substrate_(chemistry).
- Ligand_(biochemistry) wikiPageWikiLink Surface_plasmon_resonance.
- Ligand_(biochemistry) wikiPageWikiLink Van_der_Waals_force.
- Ligand_(biochemistry) wikiPageWikiLink File:Agonist_2.png.
- Ligand_(biochemistry) wikiPageWikiLink File:Agonists_v2.png.
- Ligand_(biochemistry) wikiPageWikiLink File:Myoglobin_and_heme.png.
- Ligand_(biochemistry) wikiPageWikiLinkText "Bivalent ligand".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligand (biochemistry)".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligand (biochemistry)#Privileged scaffold".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligand (biochemistry)#Receptor binding affinity".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligand (biochemistry)#Receptor.2Fligand binding affinity".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligand (biochemistry)#Receptor/ligand binding affinity".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligand (biochemistry)#Selective and non-selective".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligand (biochemistry)#binding affinity".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligand".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligand-binding".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligands".