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Matches in DBpedia 2015-10 for { ?s ?p "Traumatic Brain Injury (TBI) Modeling attempts to replicate certain aspects of TBI in order better understand what is physically happening to the brain. A variety of models can be used for this process with different models able to replicate certain aspects of TBI while also producing their own limitations.There are an estimated 1.7 million cases of TBI per year, not taking into account the lasting affects that TBI may cause. TBI is also reported to be a contributing factor in about 30% of all injury related death. Given how prevalent TBI is, preventing or minimizing its effects would benefit many people worldwide.In order to better understand what is happening during TBI, models are used to approximate the damage. Models bring both advantages and disadvantages to TBI research; on one hand brain models are very good at representing one aspect that can be observed, while on the other, aspects of the whole system must be ignored. For example, when studying blunt impacts, a neuronal cell culture model can be created that is the depth of the cortical layer. This is then subjected to different impact sizes, shapes, and forces in order to see how the cells react and what cytokines are released. This model works very well for the cortical layer, but deeper cell layers must be ignored due to the inability to oxygenate a deeper cell culture effectively. In this experiment, the disadvantage and limitation of this model is cell depth; any interactions that might occur below the cortical layer are ignored in order to gather accurate information within the cortical layer itself."@en }

• Traumatic_brain_injury_modeling abstract "Traumatic Brain Injury (TBI) Modeling attempts to replicate certain aspects of TBI in order better understand what is physically happening to the brain. A variety of models can be used for this process with different models able to replicate certain aspects of TBI while also producing their own limitations.There are an estimated 1.7 million cases of TBI per year, not taking into account the lasting affects that TBI may cause. TBI is also reported to be a contributing factor in about 30% of all injury related death. Given how prevalent TBI is, preventing or minimizing its effects would benefit many people worldwide.In order to better understand what is happening during TBI, models are used to approximate the damage. Models bring both advantages and disadvantages to TBI research; on one hand brain models are very good at representing one aspect that can be observed, while on the other, aspects of the whole system must be ignored. For example, when studying blunt impacts, a neuronal cell culture model can be created that is the depth of the cortical layer. This is then subjected to different impact sizes, shapes, and forces in order to see how the cells react and what cytokines are released. This model works very well for the cortical layer, but deeper cell layers must be ignored due to the inability to oxygenate a deeper cell culture effectively. In this experiment, the disadvantage and limitation of this model is cell depth; any interactions that might occur below the cortical layer are ignored in order to gather accurate information within the cortical layer itself.".