Matches in DBpedia 2015-10 for { ?s ?p "This gene encodes a member of the STAT-induced STAT inhibitor , also known as suppressor of cytokine signalling , family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin , GM-CSF, and interferon-gamma . The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-γ action, which is required for normal postnatal growth and survival."@en }
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- Suppressor_of_cytokine_signaling_1 summaryText "This gene encodes a member of the STAT-induced STAT inhibitor , also known as suppressor of cytokine signalling , family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin , GM-CSF, and interferon-gamma . The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-γ action, which is required for normal postnatal growth and survival.".