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DBpedia 2015-10

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Matches in DBpedia 2015-10 for { ?s ?p "The bafilomycins are a family of toxic macrolide antibiotic derived from Streptomyces griseus. These compounds all appear in the same fermentation and have quite similar biological activity. Bafilomycins are specific inhibitors of vacuolar-type H+-ATPase. The most used bafilomycin is bafilomycin A1. This is a useful tool as it can prevent the re-acidification of synaptic vesicles once they have undergone exocytosis.Bafilomycin has antibacterial, antifungal, antineoplastic, immunosuppressive activities. In addition, bafilomycin A1 has antimalarial activity It has been shown to decrease multi-drug resistance.Bafilomycin B1 has been mentioned as a potential antiosteoporotic agent in treating bone lytic diseases."@en }

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