Matches in DBpedia 2015-10 for { ?s ?p "The SUCLA2 gene encodes the beta-subunit of the ADP-forming succinyl-CoA synthetase . SCS is a mitochondrial matrix enzyme that catalyzes the reversible synthesis of succinyl-CoA from succinate and CoA. The reverse reaction occurs in the Krebs cycle, while the forward reaction may produce succinyl-CoA for activation of ketone bodies and heme synthesis. GTP-specific and ATP-specific isoforms of SCS catalyze GTP-dependent and ATP-dependent reactions, respectively. SCS is composed of an invariant alpha subunit and a beta subunit that determines the enzyme's nucleotide specificity.[supplied by OMIM]"@en }
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- SUCLA2 summaryText "The SUCLA2 gene encodes the beta-subunit of the ADP-forming succinyl-CoA synthetase . SCS is a mitochondrial matrix enzyme that catalyzes the reversible synthesis of succinyl-CoA from succinate and CoA. The reverse reaction occurs in the Krebs cycle, while the forward reaction may produce succinyl-CoA for activation of ketone bodies and heme synthesis. GTP-specific and ATP-specific isoforms of SCS catalyze GTP-dependent and ATP-dependent reactions, respectively. SCS is composed of an invariant alpha subunit and a beta subunit that determines the enzyme's nucleotide specificity.[supplied by OMIM]".