Matches in DBpedia 2015-10 for { ?s ?p "Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that exists in all eukaryotes. Its main function is to reduce errors in gene expression by eliminating mRNA transcripts that contain premature stop codons. If these aberrant mRNA transcripts were translated, the result would be deleterious gain-of-function or dominant-negative activity of the resulting proteins.The phenomenon of NMD was first described in human cells and in yeast almost simultaneously in 1979."@en }
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- Nonsense-mediated_decay comment "Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that exists in all eukaryotes. Its main function is to reduce errors in gene expression by eliminating mRNA transcripts that contain premature stop codons. If these aberrant mRNA transcripts were translated, the result would be deleterious gain-of-function or dominant-negative activity of the resulting proteins.The phenomenon of NMD was first described in human cells and in yeast almost simultaneously in 1979.".