Matches in DBpedia 2015-10 for { ?s ?p "Macrophomic acid is a fungal metabolite isolated from the fungus Macrophoma commelinae. The enzyme macrophomate synthase converts 5-acetyl-4-methoxy-6-methyl-2-pyrone to 4-acetyl-3-methoxy-5-methyl-benzoic acid (macrophomic acid) through an unusual intermolecular Diels-Alder reaction (Scheme 1). The pathway to formation of macrophomic acid suggests that the enzyme is a natural Diels-Alderase. Formation of this type of aromatic ring compound normally proceeds via the shikimate and polyketide pathways; however, the production of macrophomic acid by macrophomate synthase proceeds totally differently. Learning about the production of macrophomic acid by a possible natural Diels-Alderase enzyme is important in understanding enzyme catalytic mechanisms. This knowledge can then be applied to organic synthesis.File:Scheme 1 macrophomic acid.gif"@en }
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- Macrophomic_acid abstract "Macrophomic acid is a fungal metabolite isolated from the fungus Macrophoma commelinae. The enzyme macrophomate synthase converts 5-acetyl-4-methoxy-6-methyl-2-pyrone to 4-acetyl-3-methoxy-5-methyl-benzoic acid (macrophomic acid) through an unusual intermolecular Diels-Alder reaction (Scheme 1). The pathway to formation of macrophomic acid suggests that the enzyme is a natural Diels-Alderase. Formation of this type of aromatic ring compound normally proceeds via the shikimate and polyketide pathways; however, the production of macrophomic acid by macrophomate synthase proceeds totally differently. Learning about the production of macrophomic acid by a possible natural Diels-Alderase enzyme is important in understanding enzyme catalytic mechanisms. This knowledge can then be applied to organic synthesis.File:Scheme 1 macrophomic acid.gif".
%20through%20an%20unusual%20intermolecular%20Diels-Alder%20reaction%20(Scheme%201).%20The%20pathway%20to%20formation%20of%20macrophomic%20acid%20suggests%20that%20the%20enzyme%20is%20a%20natural%20Diels-Alderase.%20Formation%20of%20this%20type%20of%20aromatic%20ring%20compound%20normally%20proceeds%20via%20the%20shikimate%20and%20polyketide%20pathways%3B%20however%2C%20the%20production%20of%20macrophomic%20acid%20by%20macrophomate%20synthase%20proceeds%20totally%20differently.%20Learning%20about%20the%20production%20of%20macrophomic%20acid%20by%20a%20possible%20natural%20Diels-Alderase%20enzyme%20is%20important%20in%20understanding%20enzyme%20catalytic%20mechanisms.%20This%20knowledge%20can%20then%20be%20applied%20to%20organic%20synthesis.File%3AScheme%201%20macrophomic%20acid.gif%22%40en){kind=link}