Matches in DBpedia 2015-10 for { ?s ?p "Interferons induce the formation of two transcriptional activators: gamma-activating factor (GAF) and interferon-stimulated gamma factor 3 (ISGF3). A natural heterozygous germline STAT1 mutation associated with susceptibility to mycobacterial but not viral disease was found in two unrelated patients with unexplained mycobacterial disease.This mutation caused a loss of GAF and ISGF3 activation but was dominant for one cellular phenotype and recessive for the other."@en }
Showing triples 1 to 1 of
1
with 100 triples per page.
- Germline_STAT_1_Mutation comment "Interferons induce the formation of two transcriptional activators: gamma-activating factor (GAF) and interferon-stimulated gamma factor 3 (ISGF3). A natural heterozygous germline STAT1 mutation associated with susceptibility to mycobacterial but not viral disease was found in two unrelated patients with unexplained mycobacterial disease.This mutation caused a loss of GAF and ISGF3 activation but was dominant for one cellular phenotype and recessive for the other.".