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DBpedia 2015-10

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Matches in DBpedia 2015-10 for { ?s ?p "IFIT proteins (Interferon Induced proteins with Tetratricopeptide repeats) are produced in the human body and are supposed to confer immunity against viral infection. These proteins are generally produced during viral infection, Interferon (IFN) treatment, and during pathogen recognition (Pathogen associated molecular pattern recognition) by the immune system during infections. So far, four families of this protein have been identified in humans which are IFIT1, IFIT2, IFIT3 and IFIT5 and other variants have been found in different species. Birds, marsupials, frogs and fish have been found to produce only IFIT5 type proteins. These proteins differ from each other in having different numbers of tetratricopeptide repeats(TPRs). The IFIT1 is known to possess 6 TPRs and IFIT2 has 4 TPRs. The IFIT proteins that are produced in humans and mice are 40%-45% similar. It is thought that the gene encoding IFIT proteins in different species has a common ancestry."@en }

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