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DBpedia 2015-10

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Matches in DBpedia 2015-10 for { ?s ?p "Fluorine, a poisonous gas in its elemental form at biological temperatures, has been a subject of significant interest for a broad range of biological applications, including ecology, medical science, and biochemical engineering.Among the most reactive of the elements, it has proved valuable in many potent industrial compounds, such as the weak (but very toxic) acid hydrogen fluoride, which are quite dangerous to living organisms. Fluorine is a component of so-called "1080" poison, a mammal-killer banned in much of the world but still used to control populations of Australian foxes and American coyotes.Because carbon-fluorine bonds are difficult to form, they are seldom found in nature. A few species of plants and bacteria found in the tropics make fluorine-containing poisons to deter predators from eating them. The same bond makes fluorination a powerful lever for new drug design, allowing the tweaking of organic molecules in innovative ways which has led to several blockbuster commercial successes, such as Lipitor and Prozac.In dental products, when applied topically the fluoride ion chemically binds to surface tooth enamel, making it marginally more acid-resistant. Although politically controversial, fluoridation of public water supplies has shown consistent benefits to dental hygiene, especially for poor children.Manmade fluorinated compounds have also played roles in several noteworthy environmental concerns. Chlorofluorocarbons, once major components of numerous commercial aerosol products, have proven damaging to the Earth's ozone layer and resulted in the wide-reaching Montreal Protocol (though in truth the chlorine in CFCs is the destructive actor, fluorine is an important part of these molecules because it makes them very stable and long-lived). Similarly, the stability of many organofluorines has raised the issue of biopersistence. Long-lived molecules from waterproofing sprays, PFOA and PFOS, are found worldwide in wildlife and humans, including newborn children.Fluorine biology is also relevant to a number of cutting-edge technologies. PFCs (perfluorocarbons) are capable of holding enough oxygen to support human liquid breathing. Several works of science fiction have touched on this, but in the real world, researchers have experimented with PFCs for burned lung care and as blood substitutes. Fluorine in the form of its radioisotope F-18 is also at the heart of a modern medical imaging technique known as positron emission tomography (PET). A PET scan produces three-dimensional colored images of parts of the body that use a lot of sugar, particularly the brain or tumors."@en }

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